Trimetazidine Hydrochloride Impurity H

Trimetazidine Hydrochloride Impurity H is a chemical compound that is commonly used as a reference standard or impurity in the pharmaceutical industry. This impurity is essentially a by-product of the synthesis of Trimetazidine Hydrochloride, a drug that is used to treat angina pectoris and other heart-related conditions. The presence of Impurity H in Trimetazidine Hydrochloride can affect the efficacy and safety of the drug, which is why it is important to monitor its levels in pharmaceutical formulations. Chemically, Trimetazidine Hydrochloride Impurity H is also known as 2-[(2,3,4-trimethoxyphenyl)methyl]hydrazinecarboxamide hydrochloride. It is a white to off-white crystalline powder that is sparingly soluble in water and ethanol. The molecular formula of the compound is C11H16N2O3.HCl, and its molecular weight is 266.72 g/mol. In terms of usage, Trimetazidine Hydrochloride Impurity H is primarily used as a reference standard for the identification and quantification of impurities in Trimetazidine Hydrochloride formulations. It is also used as a research tool to study the synthesis and properties of related compounds. The impurity can be analyzed using various analytical techniques such as high-performance liquid chromatography (HPLC) and gas chromatography (GC). In conclusion, Trimetazidine Hydrochloride Impurity H is an important compound in the pharmaceutical industry, used as a reference standard to ensure the quality and safety of Trimetazidine Hydrochloride formulations. Its chemical properties and analytical characteristics make it an essential tool for pharmaceutical research and development.