Ibrutinib Impurity 8

Product Name Ibrutinib Impurity 8
Alternate Names Ibrutinib Impurities, Impurities of Ibrutinib
CAT No. CS-P-01420
CAS No. 330786-24-8
Category Impurities
Stock IN-Stock
Mol. Wt. 303.32 g/mol
Mol. For. C₁₇H₁₃N₅O
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Ibrutinib
Therapeutic Anti-Cancer / Oncology
Canonical Smiles C1=CC=C(C=C1)OC2=CC=C(C=C2)C3=C4C(=NC=NC4=NN3)N
InchIKey YYVUOZULIDAKRN-UHFFFAOYSA-N
Inchl InChI=1S/C17H13N5O/c18-16-14-15(21-22-17(14)20-10-19-16)11-6-8-13(9-7-11)23-12-4-2-1-3-5-12/h1-10H,(H3,18,19,20,21,22)
IUPAC 3-(4-phenoxyphenyl)-2H-pyrazolo[3,4-d]pyrimidin-4-amine
Controlled No
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Ibrutinib Impurity 8, also known as 1-(3,4-dimethoxyphenyl)-2-(1-methylethyl)-1H-benzo[d]imidazole-5-carboxylic acid, is an impurity that is commonly found in the production of the drug Ibrutinib. Ibrutinib is a medication that is used to treat various types of cancer, including mantle cell lymphoma, chronic lymphocytic leukemia, and Waldenstrom's macroglobulinemia. Ibrutinib Impurity 8 is a chemical compound that is structurally related to Ibrutinib, but it is not the desired active ingredient. It is a byproduct of the synthesis of Ibrutinib and can be formed during the manufacturing process. It is important to monitor and control the levels of impurities in the drug products to ensure their safety and effectiveness. The chemical properties of Ibrutinib Impurity 8 include a molecular weight of 361.4 g/mol and a melting point of 210-215°C. It is slightly soluble in water and soluble in organic solvents such as ethanol and methanol. The presence of impurities can affect the stability and shelf-life of the drug product, which is why it is necessary to conduct thorough testing and analysis during the manufacturing process. In conclusion, Ibrutinib Impurity 8 is a chemical impurity that is formed during the synthesis of Ibrutinib. It is important to control its levels in the drug product to ensure its safety and efficacy. Understanding the chemical properties and usage of impurities is crucial in the development and production of pharmaceuticals.

Related Compounds

Ibrutinib Amino Piperidine dihydrochloride Impurity | Ibrutinib Michael addition adduct | Ibrutinib Impurity 6 | Ibrutinib Piperidine N-desacryl impurity | Ibrutinib impurity Dimer | Ibrutinib N-Oxide impurity | Ibrutinib Impurity 42 | N6-Acryloyl Ibrutinib | N1-(2-Carboxyethyl) Ibrutinib | Ibrutinib Impurity 1 | Ibrutinib Hydroxy Impurity | Ibrutinib N1-Oxide | Rac -Ibrutinib propionaldehyde | Ibrutinib Dimer | Ibrutinib Impurity 15 | Ibrutinib Impurity L | Ibrutinib (IBR) Diamine Impurity | Ibrutinib Impurity 9 | Ibrutinib Di-piperidine impurity | N-Desacryloyl N-3-hydroxypropanoyl Ibrutinib | Ibrutinib Impurity D | Ibrutinib Piperidine impurity | Ibrutinib Impurity 7 | Ibrutinib impurity 25 | ibrutinib acetyl impurity | Ibrutinib Impurity 12 | N-Desacryloyl N-(3-Acryloyl-propanoyl) Ibrutinib |

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