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Meclozine is a medication used to treat motion sickness and vertigo. It works by blocking histamine receptors in the brain, which reduces the symptoms of nausea, dizziness, and vomiting associated with motion sickness. It is available in tablet form and is usually taken orally, with or without food.
The chemical name for meclozine is 1-(4-chlorophenyl)-phenyl-methyl-piperazine. It is classified as an antihistamine and is structurally related to other antihistamines such as diphenhydramine and promethazine. Meclozine is a white, crystalline powder that is soluble in water and ethanol.
Meclozine has a half-life of approximately 6 hours and is excreted primarily through the kidneys. It is metabolized in the liver by the cytochrome P450 enzymes, specifically CYP2D6 and CYP3A4. Meclozine should be used with caution in patients with liver or kidney disease, as well as in elderly patients or those taking other medications that can cause drowsiness.
In conclusion, meclozine is an effective medication for the treatment of motion sickness and vertigo. It works by blocking histamine receptors in the brain, which reduces symptoms of nausea, dizziness, and vomiting. Meclozine is a white, crystalline powder that is soluble in water and ethanol, and is metabolized in the liver by the cytochrome P450 enzymes. It should be used with caution in patients with liver or kidney disease, as well as in elderly patients or those taking other medications that can cause drowsiness.
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