para-Vortioxetine

Para-vortioxetine, also known as Lu AA21004, is a chemical compound that has shown promise in the treatment of major depressive disorder. It belongs to the class of drugs known as serotonin reuptake inhibitors and was developed as an improvement on the existing antidepressant drug vortioxetine. The main difference between vortioxetine and para-vortioxetine is that the latter is a more potent and selective inhibitor of the serotonin transporter. The chemical structure of para-vortioxetine consists of a core molecule of benzothiophene, which is modified by the addition of various functional groups to increase its potency and selectivity. It acts by blocking the reuptake of serotonin in the brain, thereby increasing the levels of this neurotransmitter and improving mood. The drug is typically administered orally in tablet form, with the recommended dosage being 10-20mg per day. It has a half-life of approximately 66 hours, which means that it can be taken once a day without the need for multiple dosing. Overall, para-vortioxetine shows promise as a safe and effective treatment for major depressive disorder. However, as with any medication, it is important to consult with a healthcare professional before starting this or any other antidepressant medication.