Nintedanib Carboxylic Acid
| Product Name | Nintedanib Carboxylic Acid |
|---|---|
| Alternate Names | Nintedanib Impurities, Impurities of Nintedanib |
| CAT No. | CS-P-01888 |
| CAS No. | 894783-71-2 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 525.60 g/mol |
| Mol. For. | C₃₀H₃₁N₅O₄ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Nintedanib |
| Smileys | O=C(C1=CC(NC/2=O)=C(C=C1)C2=C(NC3=CC=C(N(C)C(CN4CCN(C)CC4)=O)C=C3)/C5=CC=CC=C5)O |
| Canonical Smiles | CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)N=C(C3=CC=CC=C3)C4=C(NC5=C4C=CC(=C5)C(=O)O)O |
| InchIKey | SDJMWYVJAVLZEG-UHFFFAOYSA-N |
| Inchl | InChI=1S/C30H31N5O4/c1-33-14-16-35(17-15-33)19-26(36)34(2)23-11-9-22(10-12-23)31-28(20-6-4-3-5-7-20)27-24-13-8-21(30(38)39)18-25(24)32-29(27)37/h3-13,18,32,37H,14-17,19H2,1-2H3,(H,38,39) |
| IUPAC | 2-hydroxy-3-[N-[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]phenyl]-C-phenylcarbonimidoyl]-1H-indole-6-carboxylic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Nintedanib Carboxylic Acid is a chemical compound used in the treatment of idiopathic pulmonary fibrosis, a chronic lung disease that causes scarring of the lungs. It is an inhibitor of multiple tyrosine kinases, including vascular endothelial growth factor receptors (VEGFRs), fibroblast growth factor receptors (FGFRs), and platelet-derived growth factor receptors (PDGFRs).
Nintedanib Carboxylic Acid works by blocking the signals that stimulate the growth and proliferation of cells in the lungs, which can lead to the formation of scar tissue. This helps to slow the progression of the disease and improve lung function.
The chemical formula of Nintedanib Carboxylic Acid is C31H33N5O4, and it has a molecular weight of 539.63 g/mol. It is a white to off-white crystalline powder that is soluble in organic solvents, such as methanol and dimethyl sulfoxide.
Nintedanib Carboxylic Acid is typically administered orally in the form of capsules or tablets. The recommended dose is 150 mg twice daily, taken with food. It is important to follow the prescribed dosing regimen and to not miss any doses, as this can affect the effectiveness of the treatment.
Overall, Nintedanib Carboxylic Acid is an important medication for the treatment of idiopathic pulmonary fibrosis, and its use has been shown to improve lung function and quality of life for patients with this condition.
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Related Compounds
Nintedanib Impurity D | Nintedanib Impurity B | Nintedanib Impurity 22 | N-Desmethyl Nintedanib | Nintedanib N, N-Dimethyl amine impurity | Nintedanib DP8 | Nintedanib Impurity H | N-nitrosoacetamido-Nintedanib | N-Acetyl Nintedanib | Nintedanib DP6 | Nintedanib Methyl impurity | Nintedanib Impurity F | Nintedanib Impurity C | methyl (Z)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate | Nintedanib esylate Impurity A | Nintedanib Impurity 1 | Nintedanib Impurity 24 | Nintedanib Impurity 7 | Nintedanib 4-Nitrophenyl 2-(4-Nitroso) | Nintedanib N-desmethyl N-ethyl | Nintedanib Ethoxyenolindole | Nintedanib E-isomer (Intedanib E-isomer) | Nintedanib Impurity 28 | Nintedanib Mono N-oxide | Nintedanib acetyl impurity | Nintedanib E-Isomer | Nintedanib Impurity 15 | Nintedanib DP7 | N-Nitroso Nintedanib | Nintedanib Impurity E | Nintedanib Impurity 4 | Nintedanib Impurity 53 | Nintedanib N-Methyl Aniline Impurity | N1,N4-Bis(4-nitrophenyl)-1,4-piperazinediacetamide | Nintedanib Impurity 2 | Nintedanib Impurity 9 | Nintedanib Ethyl Ester | Nintedanib Impurity G | Nintedanib N-Acetyl Impurity | Nintedanib Impurity 25 | Nintedanib Impurity 26 | Nintedanib Impurity A | Nintedanib Impurity 33 | Nintedanib Nitroso Impurity 2 | Nintedanib Piperazinyl-N4-oxide | Nintedanib Impurity 8 | N-Propanoyl Nintedanib | Nintedanib Impurity 3 | Nintedanib Impurity 43 | Nintedanib N,N,-Dimethyl Aniline Impurity | Nintedanib Impurity 54 | Nintedanib Impurity 5 |