4-Hydroxy Fenretinide-d4

4-Hydroxy Fenretinide-d4 is a synthetic derivative of the naturally occurring retinoid, fenretinide. It is a deuterated form of 4-hydroxy fenretinide, which means that four of the hydrogen atoms in the molecule have been replaced with deuterium atoms. This modification enhances the molecule’s stability and bioavailability, making it a useful tool for research and development purposes. One of the primary uses of 4-Hydroxy Fenretinide-d4 is in pharmacokinetic studies. Its stable isotopic composition allows scientists to track the molecule’s metabolic fate in vivo, providing valuable information on its absorption, distribution, metabolism, and elimination. This data can be used to optimize dosing regimens and improve therapeutic outcomes. In addition to its pharmacokinetic applications, 4-Hydroxy Fenretinide-d4 has also been investigated for its potential as an anti-cancer agent. Fenretinide has been shown to induce apoptosis (programmed cell death) in a variety of cancer cell lines, and the deuterated derivative may offer improved efficacy and reduced toxicity compared to the parent compound. However, further research is needed to fully understand the mechanisms of action and potential clinical applications of 4-Hydroxy Fenretinide-d4. Chemically, 4-Hydroxy Fenretinide-d4 has a molecular weight of 335.47 g/mol and a chemical formula of C26H20D4NO2. It is a yellow solid that is soluble in organic solvents such as ethanol and dimethyl sulfoxide. Its purity and isotopic enrichment can be confirmed using techniques such as high-performance liquid chromatography and mass spectrometry.