4-Hydroxy Methyl Ambrisentan-D3
| Product Name | 4-Hydroxy Methyl Ambrisentan-D3 |
|---|---|
| Alternate Names | Ambrisentan Stable Isotopes, Stable Isotopes of Ambrisentan |
| CAT No. | CS-P-02879 |
| CAS No. | 1106685-66-8 (Unlabeled) |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Ambrisentan |
| Smileys | COC(C1=CC=CC=C1)(C2=CC=CC=C2)[C@@H](C(O)=O)OC3=NC(C([2H])([2H])[2H])=CC(CO)=N3 |
| Canonical Smiles | CC1=CC(=NC(=N1)OC(C(=O)O)C(C2=CC=CC=C2)(C3=CC=CC=C3)OC)CO |
| InchIKey | PDUAYPFMBRYSNN-LJQANCHMSA-N |
| Inchl | InChI=1S/C22H22N2O5/c1-15-13-18(14-25)24-21(23-15)29-19(20(26)27)22(28-2,16-9-5-3-6-10-16)17-11-7-4-8-12-17/h3-13,19,25H,14H2,1-2H3,(H,26,27)/t19-/m1/s1 |
| IUPAC | (2S)-2-[4-(hydroxymethyl)-6-methylpyrimidin-2-yl]oxy-3-methoxy-3,3-diphenylpropanoic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
4-Hydroxy Methyl Ambrisentan-D3 is a deuterated derivative of 4-Hydroxy Methyl Ambrisentan, which is a selective endothelin-A receptor antagonist used for the treatment of pulmonary arterial hypertension (PAH). It works by blocking the action of endothelin, a peptide that constricts blood vessels and increases blood pressure. By blocking endothelin-A receptors, 4-Hydroxy Methyl Ambrisentan-D3 helps to relax blood vessels, reduce blood pressure and improve blood flow, which ultimately alleviates the symptoms of PAH.
The chemical formula of 4-Hydroxy Methyl Ambrisentan-D3 is C22H15D3N2O3, and its molecular weight is 366.47 g/mol. It is a white to off-white powder, which is soluble in dimethyl sulfoxide and slightly soluble in water.
In terms of usage, 4-Hydroxy Methyl Ambrisentan-D3 is mainly used as a reference standard in analytical and bioanalytical studies. It is also used in pharmacokinetic studies to investigate the metabolism, distribution, and elimination of 4-Hydroxy Methyl Ambrisentan in the body. In addition, 4-Hydroxy Methyl Ambrisentan-D3 can be used in drug discovery and development to identify and optimize new drug candidates for the treatment of PAH.
Overall, 4-Hydroxy Methyl Ambrisentan-D3 is an important tool for researchers and scientists who are working on the development of new drugs for the treatment of PAH. Its accurate chemical and pharmacological characterization can help to advance our understanding of the disease and improve patient outcomes.
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Related Compounds
Ambrisentan acyl-β-D-glucuronide D10 | Ambrisentan D3 | rac Ambrisentan-d3 Methyl Ester | rac 4-Hydroxymethyl Ambrisentan-d3 | rac-Ambrisentan-d5 | Rac-Ambrisentan D3 | Ambrisentan D10 |