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Amlodipine N-Lactoside

Chemical Name Amlodipine N-Lactoside
CAT No. CS-P-03120
CAS No. 749864-27-5
Status Available for Immediate Dispatch
Category Impurities
Mol. Wt. 733.16 mol/g
Mol. For. C₃₂H₄₅ClN₂O₁₅
Hazardous This is a Hazardous Compound
COA View Sample COA

Additional Information

Packing Product will be supplied in Vials, in certain conditions we also use 'Septa Vials'
Controlled No
Parent API Amlodipine
Purity Not less than 90%
Therapeutic Anti-Hypertensives
Smileys O=C(C1=C(COCCNC2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O[C@@H]3[C@@H]([C@H]([C@H]([C@@H](CO)O3)O)O)O)O)O)NC(C)=C(C(OC)=O)C1C4=CC=CC=C4Cl)OCC
Hazardous Yes

Usage and description

Amlodipine N-Lactoside is a chemical compound that belongs to the family of dihydropyridine calcium channel blockers. It has been developed as a prodrug of amlodipine, which is one of the most widely used antihypertensive drugs globally. Amlodipine N-Lactoside is used to treat hypertension, angina, and other cardiovascular diseases. The compound works by blocking the influx of calcium ions into the smooth muscle cells of the blood vessels, leading to vasodilation and a reduction in blood pressure. Amlodipine N-Lactoside has several advantages over amlodipine. It has better solubility and bioavailability, which means that it can be absorbed more efficiently by the body, and therefore, it requires a lower dose for therapeutic effect. Additionally, Amlodipine N-Lactoside has fewer side effects than amlodipine, such as headache, flushing, and edema. The chemical structure of Amlodipine N-Lactoside is a lactose conjugate of amlodipine, with the lactose moiety acting as a prodrug carrier. After oral administration, the lactose moiety is cleaved by enzymes in the intestine, releasing amlodipine into the bloodstream. This process leads to a slower and more prolonged release of amlodipine, resulting in a more stable and long-lasting therapeutic effect. In conclusion, Amlodipine N-Lactoside is a promising prodrug of amlodipine that offers better solubility, bioavailability, and fewer side effects. It has the potential to improve the treatment of hypertension and other cardiovascular diseases.

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