2-Hydroxy desipramine-d6 glucuronide

Product Name 2-Hydroxy desipramine-d6 glucuronide
Alternate Names Desipramine Stable Isotopes, Stable Isotopes of Desipramine
CAT No. CS-P-07599
CAS No. 25521-31-7 (Unlabeled)
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Desipramine
Smileys CNC([2H])([2H])C([2H])([2H])C([2H])([2H])N1C2=CC=C(O[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3C(O)=O)C=C2CCC4=C1C=CC=C4
Canonical Smiles CNCCCN1C2=C(CCC3=CC=CC=C31)C=C(C=C2)OC4C(C(C(C(O4)C(=O)O)O)O)O
InchIKey XJHAOJJEVSPMBA-QMDPOKHVSA-N
Inchl InChI=1S/C24H30N2O7/c1-25-11-4-12-26-17-6-3-2-5-14(17)7-8-15-13-16(9-10-18(15)26)32-24-21(29)19(27)20(28)22(33-24)23(30)31/h2-3,5-6,9-10,13,19-22,24-25,27-29H,4,7-8,11-12H2,1H3,(H,30,31)/t19-,20-,21+,22-,24+/m0/s1
IUPAC (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[[11-[3-(methylamino)propyl]-5,6-dihydrobenzo[b][1]benzazepin-3-yl]oxy]oxane-2-carboxylic acid
Controlled No
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2-Hydroxy desipramine-d6 glucuronide is a chemical compound derived from desipramine, a tricyclic antidepressant medication. This compound is produced in the liver through glucuronidation, a process in which a glucuronic acid molecule is added to the parent drug to increase its water solubility and facilitate excretion from the body. The primary usage of 2-Hydroxy desipramine-d6 glucuronide is as a reference standard in analytical chemistry and pharmacokinetic studies. As a deuterated compound, it is used in mass spectrometry and nuclear magnetic resonance spectroscopy to identify and quantify desipramine and its metabolites in biological samples. This compound has also been used in pharmacokinetic studies to investigate the metabolism and elimination of desipramine in humans and animals. Chemically, 2-Hydroxy desipramine-d6 glucuronide is a glucuronide conjugate of 2-hydroxydesipramine, a major metabolite of desipramine. It has a molecular weight of 406.5 g/mol and a chemical formula of C17H14D6N2O7. The deuterium atoms in this compound are important for distinguishing it from other glucuronide conjugates of desipramine metabolites, which can be difficult to separate and analyze due to their similar mass and structure. In conclusion, 2-Hydroxy desipramine-d6 glucuronide is a useful reference standard for analytical chemistry and pharmacokinetic studies of desipramine and its metabolites. Its chemical properties and deuterium labeling make it a valuable tool for identifying and quantifying these compounds in biological samples.

Related Compounds

Desipramine-2,4,6,8-d4 Hydrochloride | Desipramine Hydrochloride D3 | Desipramine D3 | Desipramine D6 |

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