Dabigatran-d4

Product Name Dabigatran-d4
Alternate Names Dabigatran Stable Isotopes, Stable Isotopes of Dabigatran
CAT No. CS-P-07738
CAS No. 1618637-32-3
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 475.54 g/mol
Mol. For. C25H21D4N7O3
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Dabigatran
Therapeutic Anti-Thrombotics
Smileys CN1C2=CC=C(C(N(C3=CC=CC=N3)CCC(O)=O)=O)C=C2N=C1CNC(C([2H])=C4[2H])=C(C([2H])=C4C(N)=N)[2H]
Controlled No
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Dabigatran-d4 is a deuterated form of dabigatran, which is an oral anticoagulant medication used for the prevention of blood clots and stroke in patients with atrial fibrillation. It is also used for the treatment and prevention of deep vein thrombosis and pulmonary embolism. The chemical name of dabigatran-d4 is N-[(1S)-1-(aminocarbonyl)-2-methylpropyl]-2-[[[4-[[[(hexyloxy)carbonyl]amino]iminomethyl]phenyl]amino]methyl]-1,3-thiazole-5-carboxamide-d4. It has a molecular weight of 491.64 g/mol and a chemical formula of C25H25D4N6O3S. Dabigatran-d4 inhibits the activity of thrombin, which is a key enzyme involved in the blood coagulation process. It achieves this by binding to the active site of thrombin, thereby preventing the conversion of fibrinogen to fibrin, which is the final step in the formation of blood clots. Dabigatran-d4 is administered orally in the form of capsules and is rapidly absorbed from the gastrointestinal tract. It has a half-life of approximately 12-17 hours and is primarily eliminated by the kidneys. Due to its high specificity for thrombin, dabigatran-d4 has fewer drug interactions compared to other anticoagulants, such as warfarin. In conclusion, dabigatran-d4 is a deuterated form of dabigatran that is used as an anticoagulant medication for the prevention and treatment of blood clots and stroke. Its mechanism of action involves the inhibition of thrombin, and it has a high specificity and fewer drug interactions compared to other anticoagulants.

Related Compounds

Dabigatran D4 Etexilate | N-Nitroso Dabigatran-d4 Etexilate | Dabigatran Acyl-ß-D-glucuronide D3 trifluoroacetate salt | Deacetamidine Cyano Dabigatran-d3 Ethyl Ester Oxalate | Dabigatran Acyl-β-D-Glucuronide 13C6 | Dabigatran β-Acyl Glucuronide D4 | Dabigatran 13C6 | Deacetamidine Cyano Dabigatran-d3 Ethyl Ester | N-Nitroso Dabigatran Etexilate-d11 | N-Nitroso Dabigatran Etexilate 13C6 | Dabigatran D4 HCl | Dabigatran D7 | Dabigatran D4 DCl |

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