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N-Nitroso Rasagiline belongs to the class of drugs known as monoamine oxidase inhibitors (MAOIs). It is a potent inhibitor of the enzyme monoamine oxidase B (MAO-B). MAO-B is responsible for breaking down certain neurotransmitters in the brain, including dopamine. By inhibiting MAO-B, N-Nitroso Rasagiline increases the levels of dopamine in the brain, which can help to alleviate symptoms of Parkinson's disease.
N-Nitroso Rasagiline is generally used in the treatment of Parkinson's disease, a progressive disorder of the nervous system that affects movement. It is used as adjunct therapy to levodopa, which is the mainstay of Parkinson's disease treatment. N-Nitroso Rasagiline is also used in the treatment of depression.
Chemically, N-Nitroso Rasagiline is a derivative of Rasagiline, which is an FDA-approved drug for the treatment of Parkinson's disease. It is a yellow to orange solid that is soluble in water and organic solvents. The compound is highly reactive and can form adducts with a variety of nucleophiles, including amino acids and DNA.
The safety and efficacy of N-Nitroso Rasagiline are still being studied, and its use is currently limited to clinical trials. While early studies have shown promise, more research is needed before N-Nitroso Rasagiline can be approved for widespread use.
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