N-Nitroso Benazepril

N-Nitroso Benazepril is a chemical compound that belongs to the class of organic compounds known as nitrosamines. This compound is a derivative of Benazepril, which is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and heart failure. The nitrosamine group in N-Nitroso Benazepril is formed by the reaction of Benazepril with a nitrosating agent. N-Nitroso Benazepril is a potent carcinogen and mutagen. It is classified as a Group 2A carcinogen by the International Agency for Research on Cancer (IARC) due to its ability to cause cancer in animals and its suspected carcinogenicity in humans. The compound is also known to cause DNA damage and cell death. Due to the potential health hazards associated with N-Nitroso Benazepril, its usage is strictly regulated in many countries. The compound is not approved for use in pharmaceuticals or any other products intended for human consumption. However, it may still be present as an impurity in certain medications, particularly those manufactured in countries with less stringent regulations. In summary, N-Nitroso Benazepril is a highly toxic compound that should be avoided due to its carcinogenic and mutagenic properties. Its usage is strictly regulated, and individuals should take caution when using medications that may contain this compound as an impurity.