5,6-DIHYDROTHYMINE D3, METHYL-D3

5,6-Dihydrothymine D3, methyl-D3, also known as 5,6-dihydro-5,6-dimethylthymine, is a deuterated derivative of 5,6-dihydrothymine, a pyrimidine nucleobase found in DNA. This compound is used primarily as a stable isotope-labeled internal standard in mass spectrometry-based analytical methods for the quantification of endogenous 5,6-dihydrothymine in biological samples. The deuterium-labeled compound is particularly useful in the study of DNA damage and repair mechanisms, as well as for the evaluation of the efficacy of certain chemotherapeutic agents. Its stable isotope labeling allows for more accurate and precise quantification of endogenous 5,6-dihydrothymine levels in biological samples, which can aid in the diagnosis and treatment of various diseases. In terms of chemical information, 5,6-Dihydrothymine D3, methyl-D3 has a molecular formula of C7H10D3N2O2, a molar mass of 170.2 g/mol, and a melting point of 254-256°C. It is a white to off-white powder that is soluble in water and organic solvents such as methanol and ethanol. In conclusion, 5,6-Dihydrothymine D3, methyl-D3 is a valuable tool in the study of DNA damage and repair mechanisms, and in the diagnosis and treatment of various diseases. Its stable isotope labeling allows for more accurate and precise quantification of endogenous 5,6-dihydrothymine levels in biological samples, making it an essential component in mass spectrometry-based analytical methods.