(1R,3S)-Benazepril Hydrochloride

Product Name (1R,3S)-Benazepril Hydrochloride
Alternate Names Benazepril Impurities, Impurities of Benazepril
CAT No. CS-T-04826
CAS No. 86541-77-7
Category Impurities
Stock IN-Stock
Mol. Wt. 460.95 g/mol
Mol. For. C₂₄H₂₉ClN₂O₅
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Benazepril
Therapeutic Anti-Hypertensives
Smileys CCOC(=O)C(CCC1=CC=CC=C1)NC2CCC3=CC=CC=C3N(C2=O)CC(=O)O.Cl
Canonical Smiles CCOC(=O)C(CCC1=CC=CC=C1)NC2CCC3=CC=CC=C3N(C2=O)CC(=O)O.Cl
InchIKey VPSRQEHTHIMDQM-CMXBXVFLSA-N
Inchl InChI=1S/C24H28N2O5.ClH/c1-2-31-24(30)20(14-12-17-8-4-3-5-9-17)25-19-15-13-18-10-6-7-11-21(18)26(23(19)29)16-22(27)28;/h3-11,19-20,25H,2,12-16H2,1H3,(H,27,28);1H/t19-,20+;/m0./s1
IUPAC 2-[(3S)-3-[[(2R)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl]acetic acid;hydrochloride
Controlled No
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(1R,3S)-Benazepril Hydrochloride is a medication that belongs to the class of drugs known as angiotensin-converting enzyme (ACE) inhibitors. It is primarily used for the treatment of hypertension, heart failure, and diabetic nephropathy. It works by blocking the action of ACE, an enzyme that converts angiotensin I to angiotensin II, a potent vasoconstrictor. As a result, the medication helps to relax blood vessels and improve blood flow, thereby reducing blood pressure and improving cardiac function. Chemically, (1R,3S)-Benazepril Hydrochloride is a white or off-white crystalline powder that is soluble in water and ethanol. It has a molecular formula of C24H28N2O5.HCl and a molecular weight of 460.96 g/mol. The medication is typically administered orally in the form of tablets or capsules. The recommended dosage and duration of treatment depend on the patient's condition and medical history. (1R,3S)-Benazepril Hydrochloride is generally well-tolerated, although some patients may experience side effects such as dizziness, headache, cough, and diarrhea. Rare but serious side effects may include allergic reactions, angioedema, and renal impairment. Patients with a history of kidney disease or liver disease should use the medication with caution and under the supervision of a healthcare professional. In conclusion, (1R,3S)-Benazepril Hydrochloride is a useful medication for the treatment of hypertension, heart failure, and diabetic nephropathy. Its chemical properties and mode of action make it an effective and safe option for many patients. However, as with any medication, it should be used with caution and under the guidance of a healthcare professional.

Related Compounds

N-Nitroso Benazepril | Benazepril Impurity B |

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