(5Z)-rel-Cloprostenol Sodium

Product Name (5Z)-rel-Cloprostenol Sodium
Alternate Names Cloprostenol Impurities, Impurities of Cloprostenol
CAT No. CS-T-13225
CAS No. 55028-72-3
Category Impurities
Stock Enquire
Mol. Wt. 424.9 : 23.0 g/mol
Mol. For. C22H29ClO6 : Na
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Cloprostenol
Smileys C1C(C(C(C1O)C=CC(COC2=CC(=CC=C2)Cl)O)CC=CCCCC(=O)[O-])O.[Na+]
Canonical Smiles C1C(C(C(C1O)C=CC(COC2=CC(=CC=C2)Cl)O)CC=CCCCC(=O)[O-])O.[Na+]
InchIKey IFEJLMHZNQJGQU-KXXGZHCCSA-M
Inchl InChI=1S/C22H29ClO6.Na/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28;/h1,3,5-7,10-12,16,18-21,24-26H,2,4,8-9,13-14H2,(H,27,28);/q;+1/p-1/b3-1-,11-10+;/t16-,18-,19-,20+,21-;/m1./s1
IUPAC sodium;(Z)-7-[(1R,2R,3R,5S)-2-[(E,3R)-4-(3-chlorophenoxy)-3-hydroxybut-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoate
Controlled No
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(5Z)-rel-Cloprostenol Sodium is a synthetic analogue of the naturally occurring prostaglandin F2α. It is a potent luteolytic agent, meaning that it can induce the regression of the corpus luteum, which is a temporary endocrine structure in the ovaries that produces progesterone. This action can be used in both human and veterinary medicine. In veterinary medicine, (5Z)-rel-Cloprostenol Sodium is commonly used to synchronize estrus in cattle, sheep, and pigs, as well as to induce parturition in cows. It can also be used to treat various reproductive disorders in these animals, such as pyometra (pus-filled uterus) and cystic ovarian disease. In humans, it is used to induce abortion and to treat postpartum hemorrhage. The chemical structure of (5Z)-rel-Cloprostenol Sodium is similar to that of prostaglandin F2α, but with modifications that increase its potency and duration of action. Specifically, the addition of a cyclopentane ring and a carboxylic acid group at the 15 position enhances its stability and binding affinity to the prostaglandin F2α receptor. Overall, (5Z)-rel-Cloprostenol Sodium is a valuable tool in reproductive management in both animals and humans, with its potent luteolytic effects and enhanced chemical stability making it a highly effective agent.

Related Compounds

Cloprostenol Sodium - Impurity A (Freebase) | d-Cloprostenol Sodium Salt |

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