Ketoconazole Impurity A

Product Name Ketoconazole Impurity A
CAT No. CS-T-14910
CAS No. 254912-63-5
Category Impurities
Stock IN-Stock
Mol. Wt. 529.4 g/mol
Mol. For. C26H26Cl2N4O4
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Purity Not less than 90 %
Therapeutic Anti-Fungals
Smileys ClC1=C(C=CC(Cl)=C1)[C@@]2(O[C@@H](COC3=CC=C(N4CCN(C(C)=O)C=C4)C=C3)CO2)CN5C=CN=C5
Canonical Smiles CC(=O)N1CCN(C=C1)C2=CC=C(C=C2)OCC3COC(O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl
InchIKey GHVFISLXKPKRQU-OZXSUGGESA-N
Inchl InChI=1S/C26H26Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-10,12,14,18,23H,11,13,15-17H2,1H3/t23-,26-/m0/s1
IUPAC 1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-2,3-dihydropyrazin-1-yl]ethanone
Controlled No
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Ketoconazole Impurity A is a chemical compound that is commonly used in the manufacturing of ketoconazole, which is an antifungal medication. This impurity is a highly pure and stable form of ketoconazole that is used as a reference standard in quality control testing of ketoconazole formulations. It is also used as a chemical marker to identify the presence of impurities in the drug substance. Ketoconazole Impurity A is a white to off-white crystalline powder that has a molecular formula of C21H20Cl2N2O3. It has a melting point of 188-190°C and a purity of not less than 98%. This impurity is soluble in methanol and slightly soluble in water. Its chemical structure is similar to that of ketoconazole, and it is considered a minor impurity in the manufacturing of ketoconazole. The usage of Ketoconazole Impurity A is critical in ensuring the quality and safety of ketoconazole-based medications. It is used in the quality control testing of ketoconazole formulations to ensure that the drug is free of any impurities that could be harmful to patients. This impurity is also used in research studies to understand the chemical properties and behavior of ketoconazole. In summary, Ketoconazole Impurity A is a minor impurity that is critical in ensuring the safety and quality of ketoconazole-based medications. Its chemical properties and behavior are essential in understanding the behavior of ketoconazole, making it a valuable tool in research studies.

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