N-Desethyl Sunitinib

Product Name N-Desethyl Sunitinib
Alternate Names Sunitinib Impurities, Impurities of Sunitinib
CAT No. CS-T-15943
CAS No. 356068-97-8
Category Impurities
Stock IN-Stock
Mol. Wt. 370.4 g/mol
Mol. For. C20H23FN4O2
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Sunitinib
Purity 95%
Therapeutic Anti-Cancer / Oncology
Smileys O=C1/C(C2=CC(F)=CC=C2N1)=C\C(NC(C)=C3C(NCCNCC)=O)=C3C
Canonical Smiles CCNCCNC(=O)C1=C(NC(=C1C)C=C2C3=C(C=CC(=C3)F)NC2=O)C
InchIKey LIZNIAKSBJKPQC-GDNBJRDFSA-N
Inchl InChI=1S/C20H23FN4O2/c1-4-22-7-8-23-20(27)18-11(2)17(24-12(18)3)10-15-14-9-13(21)5-6-16(14)25-19(15)26/h5-6,9-10,22,24H,4,7-8H2,1-3H3,(H,23,27)(H,25,26)/b15-10-
IUPAC N-[2-(ethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
Controlled No
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N-Desethyl Sunitinib is a chemical compound that is commonly used as an inhibitor of multiple receptor tyrosine kinases. It is a metabolite of Sunitinib, a widely used anticancer drug. N-Desethyl Sunitinib is known to be an active metabolite of Sunitinib and has been shown to possess similar pharmacological properties as its parent compound. In terms of usage, N-Desethyl Sunitinib is used as a pharmacological tool for research purposes, particularly in the field of oncology. It is used to study the effects of Sunitinib on receptor tyrosine kinases and to investigate the potential therapeutic applications of these compounds in treating various cancers. Chemically, N-Desethyl Sunitinib is a small molecule with a molecular weight of 398.5 g/mol. It is a potent inhibitor of multiple receptor tyrosine kinases, including VEGFR, PDGFR, and c-KIT. It is also known to inhibit FLT3 and RET kinase activity, making it a promising candidate for the treatment of cancers that are driven by these kinases. Overall, N-Desethyl Sunitinib is an important chemical compound that is used in oncology research to study the effects of Sunitinib on receptor tyrosine kinases. It possesses potent inhibitory activity against multiple kinases and has potential therapeutic applications in the treatment of various cancers.

Related Compounds

N-Boc-N,N-didesethyl Sunitinib | N-Desethylsunitinib-d4 TFA Salt | Sunitinib Carboxylic Acid | Sunitinib Impurity 8 | Sunitinib Impurity I | Sunitinib Impurity C | Sunitinib formyl impurity | N-Desethylsunitinib TFA Salt | Sunitinib Impurity H | Sunitinib N-3-(Dimethylamino)propyl impurity | Sunitinib Impurity 18 | sunitinib Impurity B | Sunitinib Ketone Impurity | N-Desethyl N-Nitroso Sunitinib impurity | Sunitinib Impurity 10 | Sunitinib Impurity II (SNT 700) | Sunitinib Impurity 7 | Sunitinib Impurity 1 |

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