Des(methoxycarbonyl) Febantel

Des(methoxycarbonyl) Febantel is a potent anthelmintic agent widely used in veterinary medicine to treat parasitic infections in animals. It is a prodrug of Febantel, which is rapidly converted to the active metabolite febantel sulfone after oral administration. The active metabolite selectively targets and destroys the nerve cells of parasitic worms, resulting in their paralysis and eventual elimination from the host animal's body. Des(methoxycarbonyl) Febantel is primarily indicated for the treatment of gastrointestinal nematodes, including roundworms, hookworms, and whipworms, in dogs and cats. It is also effective against tapeworms and lungworms. The drug is available in various formulations, including tablets, suspensions, and spot-on solutions, for easy administration to animals. Chemically, Des(methoxycarbonyl) Febantel belongs to the benzimidazole-isoquinoline class of compounds. The molecular formula of the drug is C20H16N4O4S, and its molecular weight is 416.43 g/mol. The drug is slightly soluble in water and ethanol but soluble in organic solvents like chloroform and methylene chloride. Des(methoxycarbonyl) Febantel is generally safe and well-tolerated in animals when used as directed. However, like all medications, it may cause adverse effects in some animals, including vomiting, diarrhea, lethargy, and loss of appetite. It is important to follow the dosage and administration instructions provided by the veterinarian and monitor the animal's condition during and after treatment.