4-Desmethyl-2-methyl Celecoxib

Product Name 4-Desmethyl-2-methyl Celecoxib
Alternate Names Celecoxib Impurities, Impurities of Celecoxib
CAT No. CS-T-16268
CAS No. 170569-99-0
Category Impurities
Stock IN-Stock
Mol. Wt. 381.4 g/mol
Mol. For. C17H14F3N3O2S
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Celecoxib
Canonical Smiles CC1=CC=CC=C1C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F
InchIKey QGNNQDAQBISHQG-UHFFFAOYSA-N
Inchl InChI=1S/C17H14F3N3O2S/c1-11-4-2-3-5-14(11)15-10-16(17(18,19)20)22-23(15)12-6-8-13(9-7-12)26(21,24)25/h2-10H,1H3,(H2,21,24,25)
IUPAC 4-[5-(2-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
Controlled No
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4-Desmethyl-2-methyl Celecoxib, also known as DMCM, is a chemical compound that is commonly used in the pharmaceutical industry as a nonsteroidal anti-inflammatory drug (NSAID). It is a derivative of Celecoxib, which is a selective COX-2 inhibitor commonly used to treat pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, and menstrual cramps. DMCM is an active metabolite of Celecoxib that is formed in the liver. It has been found to have similar pharmacological properties to Celecoxib, including anti-inflammatory and analgesic effects. DMCM works by inhibiting the activity of cyclooxygenase-2 (COX-2), an enzyme that plays a key role in the production of prostaglandins, which are responsible for causing inflammation and pain in the body. DMCM has been shown to be effective in the treatment of various inflammatory conditions, including osteoarthritis, rheumatoid arthritis, and gout. It has also been studied for its potential use in the treatment of other conditions, such as Alzheimer's disease and cancer. In terms of chemical information, DMCM has a molecular formula of C17H14N2O2S, a molecular weight of 314.37 g/mol, and a melting point of 163-165°C. It is a white to off-white crystalline powder that is sparingly soluble in water but soluble in organic solvents such as methanol and ethanol. DMCM is typically administered orally in the form of tablets or capsules, and its dosage and duration of treatment depend on the specific condition being treated and the individual patient's response to the medication.

Related Compounds

Celecoxib Impurity 7 | Celecoxib Impurity 3 | N-NITROSOETHYLENE DIAMINO TRIACETIC ACID | N,N-DINITROSO-ETHYLENE DIAMINODIACETIC ACID | Celecoxib Impurity 21 | Celecoxib Impurity 4 | Celecoxib nitroso impurity | Celecoxib impurity 1 | Celecoxib EP Impurity B | Celecoxib EP Impurity A | Celecoxib Impurity 23 | Celecoxib Trifluro Impurity | Celecoxib Impurity 8 | Celecoxib Impurity 2 | Celecoxib Impurity 22 |

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