Ranitidine EP impurity A

Product Name Ranitidine EP impurity A
Alternate Names Ranitidine Impurities, Impurities of Ranitidine
CAT No. CS-T-19636
CAS No. 72126-78-4
Category Impurities
Stock IN-Stock
Mol. Wt. 497.67 g/mol
Mol. For. C₂₂H₃₅N₅O₄S₂
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Ranitidine
Therapeutic Anti ulcer
Smileys CN(C)CC1=CC=C(O1)CSCCNC(=C[N+](=O)[O-])NCCSCC2=CC=C(O2)CN(C)C
Canonical Smiles CN(C)CC1=CC=C(O1)CSCCNC(=C[N+](=O)[O-])NCCSCC2=CC=C(O2)CN(C)C
InchIKey VTVSRHZKBPARSF-UHFFFAOYSA-N
Inchl InChI=1S/C22H35N5O4S2/c1-25(2)13-18-5-7-20(30-18)16-32-11-9-23-22(15-27(28)29)24-10-12-33-17-21-8-6-19(31-21)14-26(3)4/h5-8,15,23-24H,9-14,16-17H2,1-4H3
IUPAC 1-N,1-N'-bis[2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethyl]-2-nitroethene-1,1-diamine
Controlled No
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Ranitidine is a popular medication used to treat various gastrointestinal disorders, including acid reflux and ulcers. Ranitidine EP impurity A, also known as N-nitrosodimethylamine (NDMA), is a chemical impurity that has been found in some batches of ranitidine products. NDMA is classified as a probable human carcinogen, meaning that it has the potential to cause cancer in humans. It is believed to form as a result of the breakdown of ranitidine in the body or during the manufacturing process. The presence of NDMA in ranitidine products has led to widespread concern and recalls of the medication. While the risk of cancer from short-term use of ranitidine containing NDMA is considered to be low, long-term exposure may pose a greater risk. It is important for healthcare professionals and patients to be aware of the potential risks associated with NDMA in ranitidine products. Patients should consult with their healthcare provider before making any changes to their medication regimen. Manufacturers of ranitidine products are working to ensure the safety of their products by implementing rigorous testing and quality control measures to detect and remove NDMA. Patients who have concerns about the safety of their medication should speak with their healthcare provider.

Related Compounds

Ranitidine N-Nitroso Impurity | Desmethyl Ranitidine | Ranitidine Related Compound A | Ranitidine Impurity F.HCl | Ranitidine N,S-Dioxide | Ranitidine EP Impurity B | Ranitidine EP Impurity J | Ranitidine Impurity 2 | Ranitidine oxalic acid | Ranitidine EP Impurity G | Ranitidine EP Impurity H | Ranitidine EP Impurity E | Ranitidine EP Impurity I | Ranitidine EP Impurity K | Ranitidine EP Impurity F | Ranitidine EP Impurity D |

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