Parahydroxy acetophenone (4-hydroxyacetophenone)

Paracetamol EP Impurity E, also known as 4-Aminophenol or p-Aminophenol, is a chemical compound that is commonly used in the production of Paracetamol, a widely used pain reliever and fever reducer. It is an organic compound with the chemical formula C6H7NO and a molecular weight of 109.13 g/mol. Paracetamol EP Impurity E is a white crystalline powder and is soluble in water and alcohol. It is used as an intermediate in the synthesis of Paracetamol, which is produced by the reaction of p-Aminophenol with acetic anhydride. The impurity is removed during the final purification process of the drug. While Paracetamol is generally considered safe for use, excessive use or overdose can lead to liver damage and other serious health complications. As such, the presence of impurities such as Paracetamol EP Impurity E must be carefully monitored and controlled during the production of the drug. In addition to its use in the production of Paracetamol, p-Aminophenol also has other applications in the pharmaceutical and chemical industries, including as a reagent in the production of dyes and other organic compounds. However, its toxicity and potential health risks must be carefully considered and addressed in any application.