Bortezomib Impurity G

Product Name Bortezomib Impurity G
Alternate Names Bortezomib Impurities, Impurities of Bortezomib
CAT No. CS-T-27112
CAS No. 289472-81-7
Category Impurities
Stock IN-Stock
Mol. Wt. t 356.42 g/mol
Mol. For. C₁₉H₂₄N₄O₃
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Bortezomib
Therapeutic Synthetic Peptides
Smileys CC(C)CC(NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)O
Canonical Smiles CC(C)CC(NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)O
InchIKey NEIDLJIPMZVISC-RDJZCZTQSA-N
Inchl InChI=1S/C19H24N4O3/c1-13(2)10-17(24)23-18(25)15(11-14-6-4-3-5-7-14)22-19(26)16-12-20-8-9-21-16/h3-9,12-13,15,17,24H,10-11H2,1-2H3,(H,22,26)(H,23,25)/t15-,17-/m0/s1
IUPAC N-[(2S)-1-[[(1S)-1-hydroxy-3-methylbutyl]amino]-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide
Controlled No
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Bortezomib Impurity G, also known as N-(3-Methoxy-4-(pyrazin-2-yl)phenyl)-2,4-dimethyl-3-oxo-3,4-dihydro-2H-pyridazine-1-carboxamide, is a chemical compound that is commonly used as a reference standard and impurity in the pharmaceutical industry. It is a synthetic derivative of Bortezomib, a proteasome inhibitor used in the treatment of multiple myeloma and mantle cell lymphoma. Bortezomib Impurity G is used to identify and quantitate Bortezomib and its related impurities in drug formulations using various analytical techniques such as high-performance liquid chromatography (HPLC), mass spectrometry (MS), and nuclear magnetic resonance (NMR) spectroscopy. It is also used to assess the stability and shelf-life of Bortezomib-containing products. Chemically, Bortezomib Impurity G is a pyridazine carboxamide derivative that belongs to the class of heterocyclic compounds. It has a molecular formula of C18H18N4O3 and a molecular weight of 346.36 g/mol. It is a crystalline solid that is soluble in organic solvents like methanol and acetonitrile. In conclusion, Bortezomib Impurity G is a valuable reference standard for the pharmaceutical industry that aids in the analysis and quality control of Bortezomib-containing products. Its chemical properties and structure make it an important analytical tool for the development and production of safe and effective medications for cancer treatment.

Related Compounds

Bortezomib Impurity 32 | N-(1-((3-methyl-1-((3aS,4S,6S,7aS)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide | Bortezomib Impurity C | Bortezomib impurity D | Bortezomib Impurity H | Bortezomib Dimer | Bortezomib N-Formyl analog | Bortezomib Impurity 10 | Bortezomib D-phenylalanyl analog | Bortezomib Hydroxy ketone analog | Bortezomib Impurity 6 | N-[2-[(3-methyl-1-oxobutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-2-Pyrazinecarboxamide | Pyrazine-2-carboxylic acid(1-(3-methyl-butylcarbamoyl)-2-phenyl-ethyl)-amide | Bortezomib Impurity 11 | Pyrazine-2-carboxylic acid [1-(1-hydroxy-3-methyl-butyl carbamoyl)-2-phenyl-ethyl]-amide | Bortezomib Impurity 29 | Bortezomib Impurity B | Pyrazine-2-carboxylic acid (1-[3-methyl-1-(2,9-dimethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.0.2.6]dec-4-yl)-butylcarbamoyl]-2-phenyl-ethyl)-amide | N-(1-(((R)-1-hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide | Bortezomib Impurity F | Hydroxy Bortezomib | Bortezomib Desphenylalanyl Analog | Bortezomib Impurity 9 | Bortezomib Impurity 55 | Bortezomib Impurity 3 (S-isomer) |

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