(S)-4-Hydroxy Mephenytoin

Product Name (S)-4-Hydroxy Mephenytoin
Alternate Names Phenytoin Impurities, Impurities of Phenytoin
CAT No. CS-T-27668
CAS No. 82695-93-0
Category Impurities
Stock IN-Stock
Mol. Wt. 234.26 g/mol
Mol. For. C₁₂H₁₄N₂O₃
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Phenytoin
Therapeutic Anticonvulsants (Anti-Epileptics)
Smileys CCC1(C(=O)N(C(=O)N1)C)C2=CC=C(C=C2)O
Canonical Smiles CCC1(C(=O)N(C(=O)N1)C)C2=CC=C(C=C2)O
InchIKey OQPLORUDZLXXPD-LBPRGKRZSA-N
Inchl InChI=1S/C12H14N2O3/c1-3-12(8-4-6-9(15)7-5-8)10(16)14(2)11(17)13-12/h4-7,15H,3H2,1-2H3,(H,13,17)/t12-/m0/s1
IUPAC (5S)-5-ethyl-5-(4-hydroxyphenyl)-3-methylimidazolidine-2,4-dione
Controlled No
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(S)-4-Hydroxy Mephenytoin is a chemical compound that belongs to the class of anticonvulsants, a group of drugs used to treat epilepsy and other seizure disorders. It is specifically used as a metabolite of mephenytoin, another anticonvulsant drug. (S)-4-Hydroxy Mephenytoin is a chiral molecule, meaning it has two mirror-image forms or enantiomers. The (S)-enantiomer is the active form of the compound, while the inactive (R)-enantiomer is eliminated from the body through metabolism. The chemical structure of (S)-4-Hydroxy Mephenytoin contains a hydroxyl group (-OH) attached to a phenyl ring. It is produced in the liver by the enzyme CYP2C19, which is responsible for the metabolism of mephenytoin. The concentration of (S)-4-Hydroxy Mephenytoin in the blood is used as a marker for CYP2C19 activity, which varies widely among individuals due to genetic differences. Clinical studies have shown that (S)-4-Hydroxy Mephenytoin has anticonvulsant properties similar to those of mephenytoin. It has also been investigated for its potential use as a biomarker for drug interactions and personalized medicine. However, its use as a therapeutic agent is limited due to its short half-life and rapid elimination from the body. Nevertheless, (S)-4-Hydroxy Mephenytoin remains an important tool in pharmacogenetic research and drug development.

Related Compounds

Phenytoin Sodium EP Impurity B | R-(-)-N-Desmethyl Mephenytoin | rac N-Desmethyl Mephenytoin | N-nitroso Mephenytoin | Phenytoin Related Compound A | Phenytoin Impurity A |

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