(Z)-4-Hydroxy Tamoxifen-d5

(Z)-4-Hydroxy Tamoxifen-d5 is a deuterated form of (Z)-4-Hydroxy Tamoxifen, a potent estrogen receptor modulator that is widely used in breast cancer treatment. This compound is labeled with five deuterium atoms, which are stable isotopes of hydrogen, making it useful for metabolic studies and drug development research. (Z)-4-Hydroxy Tamoxifen-d5 is a selective estrogen receptor modulator (SERM) that binds to the estrogen receptor (ER) and prevents the binding of estrogen to the receptor. This action blocks the growth-promoting effects of estrogen on breast cancer cells, thereby inhibiting their growth and proliferation. In addition, this compound has been shown to have antiestrogenic effects on the endometrium, which reduces the risk of endometrial cancer in women receiving tamoxifen therapy. The chemical formula of (Z)-4-Hydroxy Tamoxifen-d5 is C26H23D5NO2, and it has a molecular weight of 403.56 g/mol. This compound is a white crystalline powder that is soluble in methanol, ethanol, and dimethyl sulfoxide (DMSO). It is stable under normal conditions and can be stored at room temperature for extended periods. In conclusion, (Z)-4-Hydroxy Tamoxifen-d5 is a useful tool for researchers studying the metabolism and pharmacokinetics of tamoxifen and its derivatives. Its stable isotopic labeling allows for accurate quantification and characterization of drug metabolism, which can aid in the development of more effective breast cancer treatments.