Isonicotinic Acid

Product Name Isonicotinic Acid
Alternate Names Isoniazid Impurities, Impurities of Isoniazid
CAT No. CS-T-29791
CAS No. 55-22-1
Category Impurities
Stock IN-Stock
Mol. Wt. 123.11 g/mol
Mol. For. C₆H₅NO₂
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Isoniazid
Smileys OC(C1=CC=NC=C1)=O
Canonical Smiles C1=CN=CC=C1C(=O)O
InchIKey TWBYWOBDOCUKOW-UHFFFAOYSA-N
Inchl InChI=1S/C6H5NO2/c8-6(9)5-1-3-7-4-2-5/h1-4H,(H,8,9)
IUPAC pyridine-4-carboxylic acid
Controlled No
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Isonicotinic acid, also known as pyridine-4-carboxylic acid, is a colorless crystalline solid that is commonly used in the production of various chemicals and pharmaceuticals. It is a derivative of pyridine and contains a carboxylic acid functional group (-COOH) and an amine functional group (-NH2) on adjacent carbon atoms. One of the main uses of isonicotinic acid is as a building block for the synthesis of various drugs, particularly anti-tuberculosis drugs such as isoniazid. It is also used as a precursor for the synthesis of other pyridine derivatives, such as nicotine and various agricultural chemicals. Chemically, isonicotinic acid is a weak acid with a pKa value of 5.03. It is soluble in water and ethanol, and has a melting point of 171-173°C. It can be synthesized through a variety of methods, including the reaction of pyridine with chloroform and potassium hydroxide, or through the oxidation of 4-methylpyridine with potassium permanganate. Isonicotinic acid exhibits both acidic and basic properties, and is capable of forming salts with both acids and bases. Its chemical properties make it a versatile and important compound in the pharmaceutical and chemical industries, with numerous applications in drug development and production.

Related Compounds

N,N'-Diacety Isoniazid | Isoniazid Hydrazine | Isoniazid Dimer |

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