15-Keto Travoprost

15-Keto Travoprost is a synthetic prostaglandin F2α analogue used primarily to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. It is a potent agonist of the prostaglandin F2α receptor, which causes a decrease in intraocular pressure by increasing aqueous outflow through the trabecular meshwork and uveoscleral pathway. Chemically, 15-Keto Travoprost is a derivative of prostaglandin F2α and contains a ketone group at the 15th carbon position. This modification enhances the compound's potency and duration of action compared to other prostaglandin analogues. The molecular formula of 15-Keto Travoprost is C26H35F3O6 and its molecular weight is 500.55 g/mol. The recommended dose of 15-Keto Travoprost is one drop in the affected eye(s) once daily in the evening. It should not be used in patients who are hypersensitive to any of the ingredients in the formulation. Potential side effects of 15-Keto Travoprost include conjunctival hyperemia, eye irritation, and increased pigmentation of the iris, eyelashes, and surrounding skin. In conclusion, 15-Keto Travoprost is a potent and effective medication used to treat intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Its chemical modification enhances its potency and duration of action, making it a valuable option for patients who require long-term management of their condition.