Methotrexate EP Impurity I
| Product Name | Methotrexate EP Impurity I |
|---|---|
| Alternate Names | Methotrexate Impurities, Impurities of Methotrexate |
| CAT No. | CS-T-32161 |
| CAS No. | 66147-29-3 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 468.47 g/mol |
| Mol. For. | C₂₁H₂₄N₈O₅ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Methotrexate |
| Purity | Not less than 95% |
| Therapeutic | Immunosuppressants |
| Smileys | CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)OC |
| Canonical Smiles | CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)OC |
| InchIKey | JYFDQHNTJJOKAS-AWEZNQCLSA-N |
| Inchl | InChI=1S/C21H24N8O5/c1-29(10-12-9-24-18-16(25-12)17(22)27-21(23)28-18)13-5-3-11(4-6-13)19(32)26-14(20(33)34-2)7-8-15(30)31/h3-6,9,14H,7-8,10H2,1-2H3,(H,26,32)(H,30,31)(H4,22,23,24,27,28)/t14-/m0/s1 |
| IUPAC | (4S)-4-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]-5-methoxy-5-oxopentanoic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Methotrexate EP Impurity I is a chemical compound that is used in pharmaceutical research and development. This impurity is a known byproduct of the synthesis of Methotrexate, a chemotherapy drug used to treat a variety of cancers and autoimmune disorders. Methotrexate EP Impurity I is typically used as a reference standard in the analysis and identification of Methotrexate and its related compounds.
Chemically, Methotrexate EP Impurity I is a dihydroxymethotrexate derivative, which means that it is structurally similar to Methotrexate but contains additional hydroxyl groups. This impurity is considered to be a potential impurity in Methotrexate drug substance and drug product due to its structural similarity with Methotrexate. Therefore, it is important to monitor and control its levels during the manufacturing process.
The usage of Methotrexate EP Impurity I is critical in the quality control of Methotrexate products. It is used in the development and validation of analytical methods such as high performance liquid chromatography (HPLC) and mass spectrometry (MS) to ensure the purity and potency of Methotrexate drug products. The accurate identification and quantification of Methotrexate EP Impurity I is essential to ensure the safety and efficacy of Methotrexate therapy.
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Related Compounds
Methotrexate EP Impurity D | Methotrexate EP Impurity B (MonoHydrate) | N-Desmethyl Methotrexate dinitroso impurity | N-nitroso Methotrexate Impurity 2 | Methotrexate Nitroso Impurity 1 | N-Nitroso Methotrexate EP Impurity-L (1) | Methotrexate EP Impurity F | N-nitroso Methotrexate Ethylester impurity | Methotrexate EP Impurity A | Methotrexate EP Impurity J | N, N-Dinitroso Methotrexate EP Impurity L | N-Dinitroso Methotrexate Impurity 2 | Methotrexate EP Impurity H | R-Methotrexate di sodium | Methotrexate EP Impurity E | Methotrexate EP Impurity B Disodium salt | Methotrexate EP Impurity B | Methotrexate Dimethylamide | Methotrexate EP Impurity C | Methotrexate EP Impurity G | Methotrexate Nitroso Impurity 1 | Methotrexate diethyl ester | Methotrexate - Impurity E (HCl Salt) | N-Nitroso Methotrexate EP Impurity-B | Methotrexate EP Impurity L | N-Nitroso Methotrexate EP Impurity-L (2) |