N-Methylsulfonyl Nimesulide

Product Name N-Methylsulfonyl Nimesulide
Alternate Names Nimesulide Impurities, Impurities of Nimesulide
CAT No. CS-T-34929
CAS No. 51765-72-1
Category Impurities
Stock IN-Stock
Mol. Wt. 386.40 g/mol
Mol. For. C₁₄H₁₄N₂O₇S₂
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Nimesulide
Purity 95%
Smileys CS(=O)(N(S(=O)(C)=O)C1=CC=C([N+]([O-])=O)C=C1OC2=CC=CC=C2)=O
Canonical Smiles CS(=O)(=O)N(C1=C(C=C(C=C1)[N+](=O)[O-])OC2=CC=CC=C2)S(=O)(=O)C
InchIKey DGTALLPFLVLCNQ-UHFFFAOYSA-N
Inchl InChI=1S/C14H14N2O7S2/c1-24(19,20)16(25(2,21)22)13-9-8-11(15(17)18)10-14(13)23-12-6-4-3-5-7-12/h3-10H,1-2H3
IUPAC N-methylsulfonyl-N-(4-nitro-2-phenoxyphenyl)methanesulfonamide
Controlled No
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N-Methylsulfonyl Nimesulide (NSM) is a non-steroidal anti-inflammatory drug (NSAID) that is commonly used in the treatment of pain and inflammation. It is a derivative of nimesulide, which is known for its potent anti-inflammatory effects. NSM is a selective cyclooxygenase-2 (COX-2) inhibitor, which means it specifically targets the COX-2 enzyme that is responsible for inflammation and pain. This specificity leads to a lower risk of gastrointestinal complications compared to non-selective NSAIDs, which can inhibit both COX-1 and COX-2 enzymes. NSM is typically used to treat conditions such as rheumatoid arthritis, osteoarthritis, and other inflammatory disorders. It can also be used to manage acute pain and menstrual pain. NSM is available in various forms, including tablets and capsules. In terms of chemical information, NSM has a molecular formula of C14H14N2O6S2 and a molecular weight of 378.4 g/mol. It is a white to off-white crystalline powder that is slightly soluble in water but highly soluble in organic solvents such as ethanol and methanol. Overall, NSM is a useful NSAID that offers potent anti-inflammatory effects with a lower risk of gastrointestinal complications compared to non-selective NSAIDs. However, like all medications, it should be used under the guidance of a healthcare professional and with caution due to potential side effects and interactions with other medications.

Related Compounds

N-Nitroso Nimesulide | Amino Hydroxynimesulide NAC Adduct | Nimesulide EP Impurity E | Nimesulide Impurity D | Nimesulide EP Impurity B | Amino Nimesulide NAC Adduct Sodium Salt | Nimesulide Impurity C |

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