4-Acetaminophen D3 Sulfate

4-Acetaminophen D3 Sulfate is a deuterated form of acetaminophen sulfate, a non-opioid analgesic and antipyretic medication commonly used for the relief of mild to moderate pain and fever. This compound is used as a research tool for pharmacokinetic studies, as the deuterium label provides a unique and sensitive method for quantifying the metabolism and excretion of acetaminophen in vivo. The chemical structure of 4-Acetaminophen D3 Sulfate is C8H9D3NO4S, with a molecular weight of 215.25 g/mol. It is a white to off-white powder that is freely soluble in water and slightly soluble in ethanol and methanol. The compound is stable under normal storage conditions and has a shelf life of at least two years when stored at -20°C. In terms of pharmacological activity, 4-Acetaminophen D3 Sulfate acts by inhibiting the production of prostaglandins, which are responsible for pain and fever. It is metabolized primarily in the liver via glucuronidation and sulfation, and the deuterium label allows for precise measurement of these metabolic pathways. The compound has a half-life of approximately 2-3 hours and is excreted primarily in the urine. Overall, 4-Acetaminophen D3 Sulfate is a valuable tool for researchers studying the pharmacokinetics and metabolism of acetaminophen, and may also have potential applications in drug development and clinical trials.