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Cefaclor EP Impurity-B

Also known as: Cefaclor Impurities or impurities of Cefaclor
Chemical Name Cefaclor EP Impurity-B
CAT No. CS-T-47676
CAS Registry# 53994-69-7
Status Prompt Dispatch
Category Impurities
Mol. Wt. 234.66 g/mol
Mol. For. C₇H₇ClN₂O₃S
Hazardous This is a Hazardous Compound
COA View Sample COA

Additional Information


Controlled No
Parent API Cefaclor
Therapeutic Antibiotics, Antibiotics
Smileys OC(C(N1[C@@]2([H])[C@H](N)C1=O)=C(CS2)Cl)=O
Canonical Smiles C1C(=C(N2C(S1)C(C2=O)N)C(=O)O)Cl
InchIKey OQSAFIZCBAZPMY-AWFVSMACSA-N
Inchl InChI=1S/C7H7ClN2O3S/c8-2-1-14-6-3(9)5(11)10(6)4(2)7(12)13/h3,6H,1,9H2,(H,12,13)/t3-,6-/m1/s1
IUPAC (6R,7R)-7-amino-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Hazardous Yes


Usage and description


Cefaclor EP Impurity-B is a chemical compound that is commonly used in the pharmaceutical industry as a reference standard for the analysis and quantification of impurities in cefaclor drug substances and formulations. It is a synthetic derivative of cefaclor, a second-generation cephalosporin antibiotic, which is used to treat bacterial infections in various parts of the body, including respiratory, urinary, and skin infections. The chemical structure of Cefaclor EP Impurity-B is closely related to that of cefaclor, and it is characterized by the presence of a thiazolidine ring and a beta-lactam ring, which are the two key structural components of cephalosporin antibiotics. The purity and quality of Cefaclor EP Impurity-B are critical for ensuring the safety and efficacy of cefaclor drug products, and it is therefore subject to strict quality control measures. Chemically, Cefaclor EP Impurity-B is a white to off-white powder that is soluble in water, methanol, and acetonitrile but insoluble in chloroform and ether. It has a molecular weight of 365.83 g/mol, and its chemical formula is C16H19N3O5S. In conclusion, Cefaclor EP Impurity-B is an important reference standard that is used in the pharmaceutical industry for the analysis and quantification of impurities in cefaclor drug substances and formulations. Its chemical properties and purity make it a critical component in the quality control process for cefaclor drug products.

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