2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-d3

Product Name 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-d3
CAT No. CS-T-47940
CAS No. 210049-13-1
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Smileys NC1=NC2=C(C=C(C3=CC=CC=C3)C=N2)N1C([2H])([2H])[2H]
Canonical Smiles CN1C2=C(N=CC(=C2)C3=CC=CC=C3)N=C1N
InchIKey UQVKZNNCIHJZLS-FIBGUPNXSA-N
Inchl InChI=1S/C13H12N4/c1-17-11-7-10(9-5-3-2-4-6-9)8-15-12(11)16-13(17)14/h2-8H,1H3,(H2,14,15,16)/i1D3
IUPAC 6-phenyl-1-(trideuteriomethyl)imidazo[4,5-b]pyridin-2-amine
Controlled No
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2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-d3 is a deuterated derivative of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), a heterocyclic aromatic amine (HAA) that is formed during the cooking of meat, fish, and poultry. PhIP is a potent mutagen and carcinogen, and has been shown to induce tumors in laboratory animals. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-d3 is an isotopically labeled form of PhIP, where three hydrogen atoms are replaced with deuterium atoms. This labeling allows for more accurate mass spectroscopy analysis of PhIP in biological samples. The usage of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-d3 is primarily in research studies aimed at understanding the metabolism and toxicology of PhIP. Researchers can use this labeled compound to track the fate of PhIP in the body, measure its levels in biological samples, and study its interactions with enzymes and other biomolecules. Chemically, 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-d3 is a heterocyclic aromatic amine with a molecular formula of C14H11D3N4. It has a melting point of 147-150°C and a boiling point of 390.8°C. Its chemical structure is similar to that of PhIP, with the exception of the deuterium labeling.

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