Apafant D8

Product Name Apafant D8
CAT No. CS-T-48294
CAS No. 1185101-22-7
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Canonical Smiles CC1=NN=C2N1C3=C(C=C(S3)CCC(=O)N4CCOCC4)C(=NC2)C5=CC=CC=C5Cl
InchIKey JGPJQFOROWSRRS-JNJBWJDISA-N
Inchl InChI=1S/C22H22ClN5O2S/c1-14-25-26-19-13-24-21(16-4-2-3-5-18(16)23)17-12-15(31-22(17)28(14)19)6-7-20(29)27-8-10-30-11-9-27/h2-5,12H,6-11,13H2,1H3/i8D2,9D2,10D2,11D2
IUPAC 3-[7-(2-chlorophenyl)-13-methyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-4-yl]-1-(2,2,3,3,5,5,6,6-octadeuteriomorpholin-4-yl)propan-1-one
Controlled No
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Apafant D8 is a chemical compound that is primarily used as an antagonist to the P2Y12 receptor, which is a protein that is found on the surface of platelets. The P2Y12 receptor is responsible for mediating the activation of platelets, which is a crucial step in the formation of blood clots. Apafant D8, therefore, is used to prevent the formation of blood clots in patients who are at risk of developing thrombotic events such as myocardial infarction, stroke, and pulmonary embolism. The chemical structure of Apafant D8 is a derivative of the pyrazolo[3,4-d]pyrimidine family of compounds. It has a molecular weight of 392.5 g/mol and a melting point of 220-222°C. The compound is a white to off-white powder that is soluble in DMSO and ethanol. Apafant D8 is administered orally in the form of tablets or capsules. The recommended dose varies depending on the patient's condition and medical history. The compound is metabolized in the liver and excreted through the kidneys. The elimination half-life of Apafant D8 is approximately 12 hours. In conclusion, Apafant D8 is an important medication that is used to prevent blood clots in patients with a high risk of thrombotic events. Its chemical structure and pharmacokinetics make it a safe and effective treatment option for patients with various medical conditions.

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