Apremilast D5

Product Name Apremilast D5
Alternate Names Apremilast Stable Isotopes, Stable Isotopes of Apremilast
CAT No. CS-T-48307
CAS No. 1258597-47-5
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 465.53 g/mol
Mol. For. C₂₂H₁₉D₅N₂O₇S
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Apremilast
Purity 95%
Smileys C[S](C[C@H](C1=CC(OC([2H])([2H])C([2H])([2H])[2H])=C(OC)C=C1)N(C(C2=CC=C3)=O)C(C2=C3NC(C)=O)=O)(=O)=O
Canonical Smiles CCOC1=C(C=CC(=C1)C(CS(=O)(=O)C)N2C(=O)C3=C(C2=O)C(=CC=C3)NC(=O)C)OC
InchIKey IMOZEMNVLZVGJZ-JVFKXMKASA-N
Inchl InChI=1S/C22H24N2O7S/c1-5-31-19-11-14(9-10-18(19)30-3)17(12-32(4,28)29)24-21(26)15-7-6-8-16(23-13(2)25)20(15)22(24)27/h6-11,17H,5,12H2,1-4H3,(H,23,25)/t17-/m1/s1/i1D3,5D2
IUPAC N-[2-[(1S)-1-[4-methoxy-3-(1,1,2,2,2-pentadeuterioethoxy)phenyl]-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide
Controlled No
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Apremilast D5 is a deuterated form of Apremilast, an oral medication used to treat psoriasis and psoriatic arthritis. Apremilast D5 is a selective inhibitor of phosphodiesterase 4 (PDE4), which is an enzyme that regulates the levels of cyclic adenosine monophosphate (cAMP) in cells. By inhibiting PDE4, Apremilast D5 increases the levels of cAMP, leading to a reduction in inflammatory responses and the symptoms of psoriasis and psoriatic arthritis. Apremilast D5 is administered orally, with the recommended dosage being 30mg twice a day. It is important to take Apremilast D5 as directed by a healthcare provider, and to not exceed the recommended dosage. It may take several weeks to see the full benefits of Apremilast D5, and it should be taken consistently to maintain its effectiveness. In terms of chemical information, Apremilast D5 has a molecular formula of C22H18D5N3O4, and a molecular weight of 402.49 g/mol. It is a white to off-white crystalline powder, and is stable under normal storage conditions. Apremilast D5 is not recommended for use in pregnant or breastfeeding women, as its effects on fetal development and lactation are not well understood. Additionally, it may interact with other medications, so it is important to inform your healthcare provider of all medications you are taking before starting Apremilast D5.

Related Compounds

Apremilast D3 | Apremilast D8 |

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