Artemisinin D3

Product Name Artemisinin D3
Alternate Names Artemisinin Stable Isotopes, Stable Isotopes of Artemisinin
CAT No. CS-T-48364
CAS No. 176652-07-6
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 285.35 g/mol
Mol. For. C₁₅H₁₉D₃O₅
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Artemisinin
Smileys CC1CCC2C(C(=O)OC3C24C1CCC(O3)(OO4)C)C
Canonical Smiles CC1CCC2C(C(=O)OC3C24C1CCC(O3)(OO4)C)C
InchIKey BLUAFEHZUWYNDE-OGUHANSASA-N
Inchl InChI=1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1/i2D3
IUPAC (1R,4S,5R,8S,9R,12S,13R)-1,5-dimethyl-9-(trideuteriomethyl)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-one
Controlled No
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Artemisinin D3 is a chemical compound that is derived from the plant Artemisia annua, which is commonly known as sweet wormwood. This compound is one of the most important antimalarial drugs available today and is used in the treatment of severe and uncomplicated malaria. Artemisinin D3 is an essential component of artemisinin-based combination therapy (ACT), which is currently recommended by the World Health Organization (WHO) as the first-line treatment for malaria. The chemical structure of Artemisinin D3 is similar to that of artemisinin, which is the primary active component of the plant Artemisia annua. Artemisinin D3 is a derivative of artemisinin, in which three deuterium atoms are substituted for three hydrogen atoms. This modification enhances the mass spectrometric detection of the compound and enables the precise quantification of drug concentrations in biological samples. Artemisinin D3 works by targeting the malaria parasite within the red blood cells of the human body. The compound reacts with iron, which is released by the parasite during its digestion of hemoglobin, and produces reactive oxygen species (ROS) that damage the parasite's cell membranes and other vital structures. This leads to the death of the parasite and the eventual elimination of the infection. In summary, Artemisinin D3 is a crucial antimalarial drug that is widely used to treat malaria. Its chemical structure and mechanism of action make it an effective and safe treatment option for patients with malaria.

Related Compounds

Dihydroartemisinin 13CD3 | Dihydroartemisinin d4 | Dihydroartemisinin 13CD4 | Artemisinin-13CD3 | Dihydro Artemisinin D3 | Dihydro artemisinin-13CD4 |

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