(2R, 3S) Benazepril tert-Butyl Ester D5

Product Name (2R, 3S) Benazepril tert-Butyl Ester D5
CAT No. CS-T-48563
CAS No. 1356841-36-5
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Therapeutic Anti-Hypertensives
Canonical Smiles CCOC(=O)C(CCC1=CC=CC=C1)NC2CCC3=CC=CC=C3N(C2=O)CC(=O)OC(C)(C)C
InchIKey QNLLWVSHZXSUNF-CPHFMIRLSA-N
Inchl InChI=1S/C28H36N2O5/c1-5-34-27(33)23(17-15-20-11-7-6-8-12-20)29-22-18-16-21-13-9-10-14-24(21)30(26(22)32)19-25(31)35-28(2,3)4/h6-14,22-23,29H,5,15-19H2,1-4H3/t22-,23+/m0/s1/i6D,7D,8D,11D,12D
IUPAC ethyl (2R)-2-[[(3S)-1-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-2-oxo-4,5-dihydro-3H-1-benzazepin-3-yl]amino]-4-(2,3,4,5,6-pentadeuteriophenyl)butanoate
Controlled No
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(2R, 3S) Benazepril tert-Butyl Ester D5 is a deuterated form of Benazepril tert-Butyl Ester, which is an angiotensin-converting enzyme (ACE) inhibitor used in the treatment of hypertension and heart failure. The deuterium atoms in this compound provide additional stability and enhanced metabolic stability, making this compound useful for pharmacokinetic and pharmacodynamic studies. The chemical formula of (2R, 3S) Benazepril tert-Butyl Ester D5 is C24H28D5N3O5, and it has a molecular weight of 468.6 g/mol. The compound is a white crystalline powder that is sparingly soluble in water but soluble in organic solvents such as ethanol and methanol. The mechanism of action of (2R, 3S) Benazepril tert-Butyl Ester D5 involves the inhibition of ACE, an enzyme responsible for the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. By inhibiting ACE, this compound leads to vasodilation and a decrease in blood pressure, making it an effective treatment for hypertension. In summary, (2R, 3S) Benazepril tert-Butyl Ester D5 is a deuterated form of Benazepril tert-Butyl Ester that is commonly used for pharmacokinetic and pharmacodynamic studies. Its mechanism of action involves the inhibition of ACE, making it an effective treatment for hypertension and heart failure.

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