2-Benzyloxy Atorvastatin-d5 Acetonide tert-Butyl Ester

2-Benzyloxy Atorvastatin-d5 Acetonide tert-Butyl Ester is a chemical compound that is used in the pharmaceutical industry. This compound is a derivative of Atorvastatin, which is a medication used to treat high cholesterol levels and prevent cardiovascular diseases. The compound is labeled with deuterium, which is a stable isotope of hydrogen, to enable tracing of the compound's metabolic fate in the body. The compound has a tert-butyl ester group, which makes it more lipophilic and enhances its bioavailability. Additionally, the benzyloxy group confers stability to the compound and makes it less susceptible to degradation. The chemical structure of the compound is characterized by the presence of a lactone ring, which is crucial for the compound's pharmacological activity. In terms of usage, 2-Benzyloxy Atorvastatin-d5 Acetonide tert-Butyl Ester is commonly used in drug research and development. It is used as a reference standard for Atorvastatin metabolite analysis and is also used as an internal standard for mass spectrometry-based assays. The compound is also used in studies aimed at investigating Atorvastatin's pharmacokinetics and pharmacodynamics, including its metabolism, distribution, and excretion in the body. In conclusion, 2-Benzyloxy Atorvastatin-d5 Acetonide tert-Butyl Ester is a useful chemical compound in drug research and development. Its stable isotope labeling and lipophilic nature make it an ideal reference standard for Atorvastatin metabolite analysis. Its usage in pharmacokinetic and pharmacodynamic studies is crucial in advancing the understanding of Atorvastatin's therapeutic potential and improving patient outcomes.