rac-8,14-Bis(tert-butyldimethylsilyloxy) Efavirenz-d4
| Product Name | rac-8,14-Bis(tert-butyldimethylsilyloxy) Efavirenz-d4 |
|---|---|
| Alternate Names | Efavirenz Stable Isotopes, Stable Isotopes of Efavirenz |
| CAT No. | CS-T-49218 |
| CAS No. | 1329840-70-1 |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Efavirenz |
| Therapeutic | Antiretroviral / Anti-HIV |
| Smileys | FC(F)(F)C(C1=CC(Cl)=CC(O[Si](C)(C)C(C)(C)C)=C1NC2=O)(O2)C#CC3(C([2H])([2H])C3([2H])[2H])O[Si](C)(C)C(C)(C)C |
| Canonical Smiles | CC(C)(C)[Si](C)(C)OC1=CC(=CC2=C1NC(=O)OC2(C#CC3(CC3)O[Si](C)(C)C(C)(C)C)C(F)(F)F)Cl |
| InchIKey | CZLOCSCGTRCIBH-AREBVXNXSA-N |
| Inchl | InChI=1S/C26H37ClF3NO4Si2/c1-22(2,3)36(7,8)34-19-16-17(27)15-18-20(19)31-21(32)33-25(18,26(28,29)30)14-13-24(11-12-24)35-37(9,10)23(4,5)6/h15-16H,11-12H2,1-10H3,(H,31,32)/i11D2,12D2 |
| IUPAC | 8-[tert-butyl(dimethyl)silyl]oxy-4-[2-[1-[tert-butyl(dimethyl)silyl]oxy-2,2,3,3-tetradeuteriocyclopropyl]ethynyl]-6-chloro-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Rac-8,14-Bis(tert-butyldimethylsilyloxy) Efavirenz-d4 is a stable isotope labeled version of the antiretroviral drug Efavirenz. It is a white to off-white powder that is used primarily for research purposes.
Efavirenz is a non-nucleoside reverse transcriptase inhibitor that is used in combination with other antiretroviral drugs to treat HIV-1 infection. It works by inhibiting the reverse transcriptase enzyme, which is responsible for the replication of the virus. Efavirenz is metabolized in the liver through the cytochrome P450 system and is excreted in the urine and feces.
Rac-8,14-Bis(tert-butyldimethylsilyloxy) Efavirenz-d4 is used in pharmacokinetic studies to determine the absorption, distribution, metabolism, and excretion of Efavirenz in the body. It is also used in drug-drug interaction studies to determine how other drugs may affect the metabolism of Efavirenz.
Chemically, Rac-8,14-Bis(tert-butyldimethylsilyloxy) Efavirenz-d4 is a deuterated derivative of Efavirenz. It has a molecular formula of C40H54D4N3O5Si2 and a molecular weight of 771.17 g/mol. It is soluble in organic solvents such as methanol, ethanol, and dichloromethane.
In summary, Rac-8,14-Bis(tert-butyldimethylsilyloxy) Efavirenz-d4 is a stable isotope labeled version of the antiretroviral drug Efavirenz that is used in research to study the pharmacokinetics and drug-drug interactions of Efavirenz.
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Related Compounds
Efavirenz D5 | rac 8,14-Dihydroxy Efavirenz-d4 | rac Efavirenz D4 | rac 7-Hydroxy Efavirenz-d4 (Major) | Efavirenz 13C6 |