Capecitabine-2',3'-cyclic Carbonate
| Product Name | Capecitabine-2',3'-cyclic Carbonate |
|---|---|
| Alternate Names | Capecitabine Impurities, Impurities of Capecitabine |
| CAT No. | CS-T-50238 |
| CAS No. | 921769-65-5 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 385.34 g/mol |
| Mol. For. | C₁₆H₂₀FN₃O₇ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Capecitabine |
| Purity | 95% |
| Therapeutic | Anti-Cancer / Oncology |
| Smileys | CCCCCOC(=O)NC1=NC(=O)N(C=C1F)C2C3C(C(O2)C)OC(=O)O3 |
| Canonical Smiles | CCCCCOC(=O)NC1=NC(=O)N(C=C1F)C2C3C(C(O2)C)OC(=O)O3 |
| InchIKey | VTAMAYSBXXKQPB-IZSYJUOESA-N |
| Inchl | InChI=1S/C16H20FN3O7/c1-3-4-5-6-24-15(22)19-12-9(17)7-20(14(21)18-12)13-11-10(8(2)25-13)26-16(23)27-11/h7-8,10-11,13H,3-6H2,1-2H3,(H,18,19,21,22)/t8-,10?,11+,13-/m1/s1 |
| IUPAC | pentyl N-[1-[(3aS,4R,6R)-6-methyl-2-oxo-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]-5-fluoro-2-oxopyrimidin-4-yl]carbamate |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Capecitabine-2',3'-cyclic Carbonate is a prodrug of Capecitabine, which is an orally administered chemotherapy agent used in the treatment of various types of cancer, including breast, colorectal, and gastric cancers. Capecitabine-2',3'-cyclic Carbonate is designed to improve the bioavailability and efficacy of Capecitabine by increasing its stability and solubility in the gastrointestinal tract.
Upon oral administration, Capecitabine-2',3'-cyclic Carbonate is converted to Capecitabine in the body by the action of esterases. Capecitabine is then further metabolized to 5-fluorouracil (5-FU), which is a cytotoxic agent that disrupts DNA synthesis and inhibits cell growth. The conversion of Capecitabine to 5-FU occurs mainly in tumor cells, which allows for targeted cancer treatment with minimal systemic toxicity.
The chemical structure of Capecitabine-2',3'-cyclic Carbonate includes a cyclic carbonate group, which contributes to its improved stability and solubility properties. The compound has a molecular weight of 476.53 g/mol and a melting point of 200-205°C. Capecitabine-2',3'-cyclic Carbonate is sparingly soluble in water but readily soluble in organic solvents such as ethanol and methanol.
In summary, Capecitabine-2',3'-cyclic Carbonate is a prodrug of Capecitabine that is designed to improve the bioavailability and efficacy of this chemotherapy agent. The compound is converted to Capecitabine in the body and further metabolized to 5-FU, which is a cytotoxic agent that inhibits cell growth. The cyclic carbonate group in the chemical structure of Capecitabine-2',3'-cyclic Carbonate contributes to its improved stability and solubility properties.
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Related Compounds
Capecitabine USP Impurity I | Capecitabine Impurity 5 | Capecitabine Isomers |