(R,S)-Cotinine-d3 N-Oxide

(R,S)-Cotinine-d3 N-Oxide is a stable isotope-labeled compound used in scientific research for a variety of purposes. It is a derivative of cotinine, which is a metabolite of nicotine found in the urine of smokers and is often used as a biomarker for tobacco exposure. The d3 designation in the name of this compound indicates that it is labeled with three deuterium atoms, which are heavy isotopes of hydrogen. This labeling allows for the compound to be distinguished from the non-labeled version in experiments. (R,S)-Cotinine-d3 N-Oxide can be used as an internal standard in mass spectrometry-based assays for the quantification of cotinine and its derivatives in biological samples. It can also be used in pharmacokinetic studies to track the metabolism and elimination of nicotine and its metabolites in the body. Additionally, this compound can be used in studies investigating the role of cotinine and nicotine in addiction, as well as in the development of new treatments for smoking cessation. Chemically, (R,S)-Cotinine-d3 N-Oxide has a molecular formula of C10H9D3N2O2 and a molecular weight of 206.23 g/mol. Its structure consists of a pyridine ring, a pyrrolidine ring, and an N-oxide group. The compound is white to off-white in color and is typically supplied as a powder. It is stable under normal storage conditions and is soluble in organic solvents such as methanol and acetonitrile.