Dapagliflozin D5

Product Name Dapagliflozin D5
Alternate Names Dapagliflozin Stable Isotopes, Stable Isotopes of Dapagliflozin
CAT No. CS-T-51602
CAS No. 1204219-80-6
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 413.90 g/mol
Mol. For. C₂₁H₂₀D₅ClO₆
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Dapagliflozin
Purity 95%
Therapeutic Anti-Diabetic
Smileys O[C@H]1[C@H](C2=CC(CC3=CC=C(OC([2H])([2H])C([2H])([2H])[2H])C=C3)=C(Cl)C=C2)O[C@H](CO)[C@@H](O)[C@@H]1O
Canonical Smiles CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C3C(C(C(C(O3)CO)O)O)O)Cl
InchIKey JVHXJTBJCFBINQ-CAXKFZQOSA-N
Inchl InChI=1S/C21H25ClO6/c1-2-27-15-6-3-12(4-7-15)9-14-10-13(5-8-16(14)22)21-20(26)19(25)18(24)17(11-23)28-21/h3-8,10,17-21,23-26H,2,9,11H2,1H3/t17-,18-,19+,20-,21+/m1/s1/i1D3,2D2
IUPAC (2S,3R,4R,5S,6R)-2-[4-chloro-3-[[4-(1,1,2,2,2-pentadeuterioethoxy)phenyl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol
Controlled No
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Dapagliflozin D5 is a stable isotope labeled version of the drug dapagliflozin, which is used to treat type 2 diabetes. It works by blocking the SGLT2 protein in the kidneys, which reduces the amount of glucose that is reabsorbed into the bloodstream. This leads to increased glucose excretion in urine and lower blood sugar levels in the body. Dapagliflozin D5 is primarily used in clinical research studies to study the pharmacokinetics, pharmacodynamics, and metabolism of dapagliflozin. The stable isotope labeling allows for accurate quantification and tracking of the drug and its metabolites in biological samples, which can provide valuable insights into drug efficacy and safety. Chemically, dapagliflozin D5 is a sodium-glucose co-transporter 2 (SGLT2) inhibitor with a molecular formula of C21H22CIN6O5S2D5Na. Its molecular weight is 510.0 g/mol. The drug is typically administered orally as a tablet, with dosages ranging from 5-10mg per day depending on the patient's individual needs. While dapagliflozin D5 is not commonly used in clinical practice, its use in research studies can provide important information for improving the treatment of type 2 diabetes and other related conditions.

Related Compounds

Dapagliflozin D4 | Dapagliflozin 13C6 | Dapagliflozin-6-13C | Dapagliflozin 3-O-β-D-Glucuronide D5 | Dapagliflozin D7 |

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