2-Desfluoro Fluconazole

2-Desfluoro Fluconazole is a derivative of fluconazole, which is a triazole antifungal medication used to treat various fungal infections. It is known to be effective against a wide range of fungal infections, including candidiasis, cryptococcosis, and dermatophytosis. 2-Desfluoro Fluconazole is a potent inhibitor of fungal cytochrome P450-dependent enzymes, which are necessary for the biosynthesis of ergosterol, a key component of the fungal cell membrane. By inhibiting this enzyme, 2-Desfluoro Fluconazole prevents the growth and replication of fungi, leading to the elimination of the infection. Chemically, 2-Desfluoro Fluconazole is a white crystalline powder with a molecular formula of C13H12F2N6O. It has a molecular weight of 306.28 g/mol and a melting point of 208-210°C. It is soluble in organic solvents like methanol, ethanol, and acetonitrile but is relatively insoluble in water. 2-Desfluoro Fluconazole is primarily used as an antifungal medication in the treatment of systemic fungal infections. It is available in various forms like tablets, oral suspensions, and injections. The dosage and duration of treatment depend on the severity of the infection, the age, weight, and overall health of the patient, and any other underlying medical conditions. While generally safe, 2-Desfluoro Fluconazole may cause side effects like nausea, vomiting, diarrhea, and rash. It is important to follow the prescribed dosage and consult a healthcare professional if any adverse reactions occur.