2’-O-(5’-Deoxy-β-D-ribofuranosyl) Capecitabine

Product Name 2’-O-(5’-Deoxy-β-D-ribofuranosyl) Capecitabine
Alternate Names Capecitabine Impurities, Impurities of Capecitabine
CAT No. CS-T-52017
CAS No. 1262133-66-3
Category Impurities
Stock IN-Stock
Mol. Wt. 475.5 g/mol
Mol. For. C20H30FN3O9
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Capecitabine
Purity Not less than 95%
Therapeutic Anti-Cancer / Oncology
Smileys CCCCCOC(=O)NC1=NC(=O)N(C=C1F)C2C(C(C(O2)C)O)OC3C(C(C(O3)C)O)O
Controlled No
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2’-O-(5’-Deoxy-β-D-ribofuranosyl) Capecitabine is a prodrug used in the treatment of breast, colon, and gastric cancer. It is an oral chemotherapy agent that is converted to its active form, 5-fluorouracil (5-FU), by a series of enzymatic reactions in the body. The conversion process involves the removal of the 5’-deoxy group from the ribose sugar, followed by the sequential addition of three phosphate groups to the molecule. Once converted to 5-FU, the drug inhibits the synthesis of DNA and RNA, thereby preventing the growth and division of cancer cells. The chemical structure of 2’-O-(5’-Deoxy-β-D-ribofuranosyl) Capecitabine consists of a fluoropyrimidine nucleoside analog linked to a 5’-deoxyribose sugar moiety. The drug is administered orally and is rapidly absorbed from the gastrointestinal tract. The pharmacokinetics of the drug are complex and depend on several factors, including the patient’s age, body weight, and renal function. Despite its efficacy in the treatment of cancer, 2’-O-(5’-Deoxy-β-D-ribofuranosyl) Capecitabine can cause several adverse effects, including gastrointestinal toxicity, hand-foot syndrome, and myelosuppression. Patients receiving the drug require careful monitoring and management of side effects to ensure optimal treatment outcomes. Overall, 2’-O-(5’-Deoxy-β-D-ribofuranosyl) Capecitabine is a valuable treatment option for cancer patients and is an important component of many chemotherapy regimens.

Related Compounds

Capecitabine Impurity 5 | Capecitabine-2',3'-cyclic Carbonate | Capecitabine Isomers | Capecitabine USP Impurity I |

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