3’-O-(5’-Deoxy-β-D-ribofuranosyl) Capecitabine
| Product Name | 3’-O-(5’-Deoxy-β-D-ribofuranosyl) Capecitabine |
|---|---|
| Alternate Names | Capecitabine Impurities, Impurities of Capecitabine |
| CAT No. | CS-T-52018 |
| CAS No. | 1262133-64-1 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 475.47 g/mol |
| Mol. For. | C₂₀H₃₀FN₃O₉ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Capecitabine |
| Purity | Not less than 90 % |
| Therapeutic | Anti-Cancer / Oncology |
| Smileys | CCCCCOC(=O)NC1=NC(=O)N(C=C1F)C2C(C(C(O2)C)OC3C(C(C(O3)C)O)O)O |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
3’-O-(5’-Deoxy-β-D-ribofuranosyl) Capecitabine is a potent anticancer drug that is used for the treatment of various types of cancer, including colon, breast, and pancreatic cancer. It is a prodrug that is metabolized in the body to form 5-fluorouracil (5-FU), a chemotherapeutic agent that inhibits the growth of cancer cells.
The drug works by interfering with the synthesis of DNA and RNA, which are essential for the growth and division of cancer cells. It also inhibits the activity of thymidylate synthase, an enzyme that is necessary for the production of thymidine, a building block of DNA. This leads to the accumulation of toxic metabolites in cancer cells, which ultimately results in their death.
3’-O-(5’-Deoxy-β-D-ribofuranosyl) Capecitabine is administered orally and is rapidly absorbed into the bloodstream. It is converted to 5-FU in the liver and tumors, where it exerts its cytotoxic effects. The drug has a relatively short half-life of about 30 minutes, which means that it needs to be taken multiple times a day to maintain therapeutic levels in the body.
In terms of chemical information, 3’-O-(5’-Deoxy-β-D-ribofuranosyl) Capecitabine is a derivative of the nucleoside analog cytidine. It has a molecular weight of 359.3 g/mol and a chemical formula of C15H22FN3O6. The drug is available under the brand name Xeloda and is typically prescribed in combination with other chemotherapy drugs for maximum efficacy.
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Related Compounds
Capecitabine Isomers | Capecitabine Impurity 5 | Capecitabine USP Impurity I | Capecitabine-2',3'-cyclic Carbonate |