2-Deoxyuridine-3 13C

Product Name 2-Deoxyuridine-3 13C
Alternate Names Uridine Stable Isotopes, Stable Isotopes of Uridine
CAT No. CS-T-52048
CAS No. 478510-89-3
Category Stable Isotopes
Stock Enquire
Mol. Wt. 229.19 g/mol
Mol. For. C¹³CH12N2O5
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Uridine
Canonical Smiles C1C(C(OC1N2C=CC(=O)NC2=O)CO)O
InchIKey MXHRCPNRJAMMIM-HOSGXKPLSA-N
Inchl InChI=1S/C9H12N2O5/c12-4-6-5(13)3-8(16-6)11-2-1-7(14)10-9(11)15/h1-2,5-6,8,12-13H,3-4H2,(H,10,14,15)/t5-,6+,8+/m0/s1/i5+1
IUPAC 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)(413C)oxolan-2-yl]pyrimidine-2,4-dione
Controlled No
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2-Deoxyuridine-3 13C is a stable isotope-labeled nucleoside that is widely used in biochemical research. It is a modified form of thymidine that contains a carbon-13 isotope in the third position of the deoxyribose sugar. This stable isotope labeling allows for precise tracking and analysis of nucleotide metabolism in living cells. 2-Deoxyuridine-3 13C is commonly used in DNA replication studies, as it is incorporated into newly synthesized DNA strands during cell division. This allows researchers to follow the fate and turnover of DNA within cells, as well as to study the mechanisms of DNA damage and repair. In addition to its use in DNA replication studies, 2-Deoxyuridine-3 13C is also used in cancer research. Cancer cells frequently exhibit altered nucleotide metabolism, and the use of stable isotope labeling can help researchers to better understand these metabolic changes and develop new therapeutic strategies. From a chemical standpoint, 2-Deoxyuridine-3 13C is a nucleoside composed of a deoxyribose sugar, a nitrogenous base (uracil), and a carbon-13 isotope. It is typically synthesized using a combination of chemical and enzymatic methods, and is available commercially from a variety of sources. Its stable isotope labeling makes it a powerful tool for studying nucleotide metabolism and DNA replication in living cells.

Related Compounds

Trifluridine 13C15N2 | Uridine-5,6-d2 | Tetrahydro uridine D3 | Uridine-3’,5’-cyclic-13C5 Monophosphate Sodium Salt | Uridine-[5',5'-D2] | Uridine-2 13C-1,3 15N2 | Ara-uridine 13C5 | Ara-uridine-5'-monophosphate disodium salt 13C,15N2 | Uridine 5'-Diphospho-a-D-glucose 13C6 Diammonium Salt |

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