Diazoxide D3

Product Name Diazoxide D3
CAT No. CS-T-52466
CAS No. 1432063-51-8
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 233.69 g/mol
Mol. For. C₈H₄D₃ClN₂O₂S
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Smileys CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl
Canonical Smiles CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl
InchIKey GDLBFKVLRPITMI-FIBGUPNXSA-N
Inchl InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)/i1D3
IUPAC 7-chloro-3-(trideuteriomethyl)-4H-1lambda6,2,4-benzothiadiazine 1,1-dioxide
Controlled No
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Diazoxide D3 is a synthetic drug that acts as a potassium channel activator. It is used primarily in the treatment of high blood pressure, specifically in patients with hypertension associated with insulin resistance. It is also used in the management of hypoglycemia, a condition where blood sugar levels drop below normal levels, in patients with hyperinsulinism. The chemical name of Diazoxide D3 is 7-chloro-3-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one-1,1-dioxide. It is a white crystalline powder with a molecular weight of 274.18 g/mol. Diazoxide D3 is soluble in water, ethanol, and methanol. Diazoxide D3 works by opening the ATP-sensitive potassium channels in the smooth muscle cells of blood vessels. The opening of these channels leads to relaxation of the smooth muscle, which in turn results in dilation of the blood vessels. This dilation reduces the resistance to blood flow, thereby lowering blood pressure. In addition to its blood pressure lowering effects, Diazoxide D3 also reduces insulin secretion from the pancreas. This makes it useful in the treatment of hyperinsulinism, a condition where the body produces too much insulin, leading to low blood sugar levels. While Diazoxide D3 is generally well-tolerated, it may cause side effects such as dizziness, nausea, and headache. It should not be used in patients with a known allergy to the drug or those with low blood pressure.

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