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N-(2,6-Dimethylphenyl)acetamide-d3 is a deuterated form of N-(2,6-Dimethylphenyl)acetamide, a chemical compound with the molecular formula C11H14NO. It is commonly used in pharmaceutical and chemical research as a stable isotope-labeled internal standard for quantitative analysis by mass spectrometry.
N-(2,6-Dimethylphenyl)acetamide-d3 contains three deuterium atoms, which replace three hydrogen atoms in the parent compound. This makes it useful as a reference standard for quantification in mass spectrometry-based experiments. It is also useful in pharmacokinetic studies, where it is used as a tracer to monitor the distribution, metabolism, and excretion of drugs.
The chemical properties of N-(2,6-Dimethylphenyl)acetamide-d3 are similar to those of the non-deuterated compound. It is a white to off-white crystalline powder that is soluble in organic solvents such as methanol and dichloromethane. It has a melting point of 86-88°C and a boiling point of 306-308°C.
In conclusion, N-(2,6-Dimethylphenyl)acetamide-d3 is a valuable reagent in pharmaceutical and chemical research. Its stability and predictable behavior make it an ideal internal standard for mass spectrometry-based quantification. Its deuterated form allows for accurate and precise measurements in pharmacokinetic studies, aiding in the development of new drugs and therapies.
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