5a-Dihydrocortisol

Product Name 5a-Dihydrocortisol
CAT No. CS-T-53031
CAS No. 516-41-6
Category Impurities
Stock IN-Stock
Mol. Wt. 364.48 g/mol
Mol. For. C₂₁H₃₂O₅
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Canonical Smiles CC12CCC(=O)CC1CCC3C2C(CC4(C3CCC4(C(=O)CO)O)C)O
InchIKey ACSFOIGNUQUIGE-SERXDUEGSA-N
Inchl InChI=1S/C21H32O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h12,14-16,18,22,24,26H,3-11H2,1-2H3/t12-,14-,15-,16-,18+,19-,20-,21-/m0/s1
IUPAC (5S,8S,9S,10S,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-one
Controlled No
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5a-Dihydrocortisol, also known as 5a-tetrahydrocortisol or THF, is a steroid hormone that is naturally produced in the body by the adrenal gland. It is a derivative of cortisol, which is a hormone that helps to regulate the body's stress response and metabolism. 5a-Dihydrocortisol is often used in medical research as a reference standard for the measurement of cortisol levels in the body. Chemically, 5a-Dihydrocortisol is a 21-carbon steroid with a hydroxyl group at position 11 and a double bond between positions 4 and 5. It is synthesized from cortisol by the action of the enzyme 5α-reductase, which reduces the double bond between positions 4 and 5. This conversion is important for the metabolism of cortisol, as it allows the hormone to be excreted from the body. In medical research, 5a-Dihydrocortisol is often used as a reference standard for the measurement of cortisol levels in the body. This is because it is less active than cortisol and is easier to measure accurately. In addition, 5a-Dihydrocortisol is used to study the effects of cortisol on the body, as well as the role of cortisol in various diseases and conditions. Overall, 5a-Dihydrocortisol is an important hormone in the body that is involved in the regulation of stress response and metabolism. Its chemical structure and function make it a valuable tool for medical research, particularly in the study of cortisol levels in the body.

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