3,5-Dimethyl-4-hydroxybenzonitrile D8

3,5-Dimethyl-4-hydroxybenzonitrile D8, also known as 3,5-DM-4-HBN D8, is a deuterated analogue of 3,5-dimethyl-4-hydroxybenzonitrile (3,5-DM-4-HBN). This compound is widely used in the pharmaceutical industry as a key intermediate in the synthesis of several drugs, including anti-inflammatory agents, antihistamines, and analgesics. The chemical formula for 3,5-DM-4-HBN D8 is C9H5D8NO, and its molecular weight is 149.25 g/mol. This compound is a white to off-white crystalline powder that is soluble in polar solvents such as methanol, ethanol, and acetone. Its melting point is reported to be between 130-135°C. The deuterium labeling in 3,5-DM-4-HBN D8 provides several advantages over its non-deuterated analogue. Firstly, it enhances the stability of the compound in biological systems, as deuterium is less likely to undergo metabolic degradation compared to hydrogen. Additionally, deuterium labeling can improve the pharmacokinetic properties of drugs by increasing their half-life and reducing their clearance rate. In conclusion, 3,5-Dimethyl-4-hydroxybenzonitrile D8 is a valuable compound in the pharmaceutical industry due to its versatile applications as an intermediate in drug synthesis. Its deuterium labeling provides several advantages over its non-deuterated analogue, making it a useful tool for drug development and research.