D-erythro-N,N-Dimethylsphingosine-d6

D-erythro-N,N-Dimethylsphingosine-d6 is a deuterium-labeled analogue of sphingosine, a type of sphingolipid that is present in cell membranes and involved in various cellular processes. This compound is used in research as a stable isotope-labeled internal standard for the quantification of sphingosine and related lipids using mass spectrometry-based methods. The chemical formula of D-erythro-N,N-Dimethylsphingosine-d6 is C18H41D6NO2, and its molecular weight is 311.6 g/mol. It is a white powder that is soluble in organic solvents such as methanol, chloroform, and dichloromethane. In terms of its chemical properties, D-erythro-N,N-Dimethylsphingosine-d6 is a sphingoid base with a long hydrophobic chain consisting of 18 carbon atoms and a polar head group containing a primary amino group and a secondary hydroxyl group. The deuterium atoms are incorporated into the two methyl groups attached to the amino group, which makes this compound useful for isotope dilution mass spectrometry. Overall, D-erythro-N,N-Dimethylsphingosine-d6 is an important tool in lipidomics research and provides a reliable means of quantitative analysis of sphingolipids. Its stable isotope labeling allows for accurate quantification of sphingosine levels in biological samples and helps to elucidate the role of sphingolipids in various physiological and pathological conditions.