Drospirenone 5,5-Diol

Product Name Drospirenone 5,5-Diol
Alternate Names Drospirenone Impurities, Impurities of Drospirenone
CAT No. CS-T-53997
CAS No. 863329-70-8
Category Impurities
Stock IN-Stock
Mol. Wt. Not Available
Mol. For. C24H34O4
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Drospirenone
Smileys CC12CCC(=O)CC1(C3CC3C4C2CCC5(C4C6CC6C57CCC(O7)O)C)O
Canonical Smiles CC12CCC(=O)CC1(C3CC3C4C2CCC5(C4C6CC6C57CCC(O7)O)C)O
InchIKey GOSKJECPIJLTSX-FNUWZBOWSA-N
Inchl InChI=1S/C24H34O4/c1-21-6-3-12(25)11-23(21,27)16-9-13(16)19-15(21)4-7-22(2)20(19)14-10-17(14)24(22)8-5-18(26)28-24/h13-20,26-27H,3-11H2,1-2H3/t13-,14+,15+,16+,17-,18?,19+,20+,21+,22-,23+,24-/m0/s1
IUPAC (1R,2R,4R,5R,10R,11R,14S,15S,16S,18S,19R)-5,5'-dihydroxy-10,14-dimethylspiro[hexacyclo[9.8.0.02,4.05,10.014,19.016,18]nonadecane-15,2'-oxolane]-7-one
Controlled No
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Drospirenone 5,5-Diol is a synthetic progestin used in hormonal contraceptives and hormone replacement therapies. It is a derivative of spironolactone, a diuretic and aldosterone antagonist, and has a similar structure to progesterone. Drospirenone 5,5-Diol functions as an anti-androgen and has minimal estrogenic or androgenic activity. Drospirenone 5,5-Diol is commonly used in combination with ethinyl estradiol, an estrogen, in oral contraceptive pills. The combination of these hormones prevents ovulation and thickens cervical mucus, making it more difficult for sperm to reach the uterus. Drospirenone 5,5-Diol has also been used in hormone replacement therapy for postmenopausal women to alleviate symptoms such as hot flashes and vaginal dryness. In addition to its contraceptive and hormone replacement therapy applications, Drospirenone 5,5-Diol has also been studied for its potential use in treating acne and hirsutism (excessive hair growth). It has been shown to reduce sebum production and inhibit the activity of androgens, which can contribute to these conditions. Chemically, Drospirenone 5,5-Diol is a synthetic steroidal compound with a molecular weight of 366.5 g/mol. It has a melting point of around 200-202°C and is soluble in acetone, ethanol, and chloroform. The half-life of Drospirenone 5,5-Diol in the body is approximately 30 hours. It is metabolized in the liver and excreted in urine and feces.

Related Compounds

Drospirenone EP Impurity F | Drospirenone Ether Impurity | Drospirenone EP Impurity B | Drospirenone EP Impurity I |

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